Alberto Inga
Overview
Explore the profile of Alberto Inga including associated specialties, affiliations and a list of published articles.
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108
Citations
2590
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Recent Articles
11.
Valentini S, Marchioretti C, Bisio A, Rossi A, Zaccara S, Romanel A, et al.
iScience
. 2021 Dec;
24(12):103531.
PMID: 34917903
Few studies have explored the association between SNPs and alterations in mRNA translation potential. We developed an approach to identify SNPs that can mark allele-specific protein expression levels and could...
12.
Ciani Y, Fedrizzi T, Prandi D, Lorenzin F, Locallo A, Gasperini P, et al.
Cell Syst
. 2021 Nov;
13(2):183-193.e7.
PMID: 34731645
Pan-cancer studies sketched the genomic landscape of the tumor types spectrum. We delineated the purity- and ploidy-adjusted allele-specific profiles of 4,950 patients across 27 tumor types from the Cancer Genome...
13.
Rossi A, Inga A
Methods Mol Biol
. 2021 Oct;
2404:157-165.
PMID: 34694608
RNA is never left alone throughout its life cycle. Together with proteins, RNAs form membraneless organelles, called ribonucleoprotein particles (RNPs) where these two types of macromolecules strongly influence each other's...
14.
Bosco B, Rossi A, Rizzotto D, Hamadou M, Bisio A, Giorgetta S, et al.
Cancers (Basel)
. 2021 Sep;
13(17).
PMID: 34503222
DHX30 was recently implicated in the translation control of mRNAs involved in p53-dependent apoptosis. Here, we show that DHX30 exhibits a more general function by integrating the activities of its...
15.
Gomes A, Ramos H, Inga A, Sousa E, Saraiva L
Cancers (Basel)
. 2021 Jul;
13(13).
PMID: 34283062
p53 is a transcription factor with a pivotal role in cell homeostasis and fate. Its impairment is a major event in tumor onset and development. In fact, about half of...
16.
Ramos H, Soares M, Silva J, Raimundo L, Calheiros J, Gomes C, et al.
Cell Rep
. 2021 Apr;
35(2):108982.
PMID: 33852837
Impairment of the p53 pathway is a critical event in cancer. Therefore, reestablishing p53 activity has become one of the most appealing anticancer therapeutic strategies. Here, we disclose the p53-activating...
17.
Monti P, Brazda V, Bohalova N, Porubiakova O, Menichini P, Speciale A, et al.
Genes (Basel)
. 2021 Mar;
12(2).
PMID: 33672023
P53, P63, and P73 proteins belong to the P53 family of transcription factors, sharing a common gene organization that, from the P1 and P2 promoters, produces two groups of mRNAs...
18.
Senitzki A, Safieh J, Sharma V, Golovenko D, Danin-Poleg Y, Inga A, et al.
Nucleic Acids Res
. 2021 Jan;
49(3):1364-1382.
PMID: 33444431
Sequence-specific protein-DNA interactions are at the heart of the response of the tumor-suppressor p53 to numerous physiological and stress-related signals. Large variability has been previously reported in p53 binding to...
19.
Lauria F, Bernabo P, Tebaldi T, Groen E, Perenthaler E, Maniscalco F, et al.
Nat Cell Biol
. 2020 Sep;
22(10):1239-1251.
PMID: 32958857
The contribution of ribosome heterogeneity and ribosome-associated proteins to the molecular control of proteomes in health and disease remains unclear. Here, we demonstrate that survival motor neuron (SMN) protein-the loss...
20.
Rizzotto D, Zaccara S, Rossi A, Dassi E, Inga A
Mol Cell Oncol
. 2020 Sep;
7(5):1767483.
PMID: 32944629
The search for mechanisms underlying different cellular responses to the treatment with Nutlin-3, an MDM2 inhibitor that unleashes p53, revealed a translational control mechanism involving the RNA binding proteins PCBP2...