Alberto Elosegui-Artola
Overview
Explore the profile of Alberto Elosegui-Artola including associated specialties, affiliations and a list of published articles.
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38
Citations
2786
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Recent Articles
1.
Maiques O, Sallan M, Laddach R, Pandya P, Varela A, Crosas-Molist E, et al.
Nat Commun
. 2025 Feb;
16(1):1394.
PMID: 39952917
The extracellular matrix (ECM) controls tumour dissemination. We characterise ECM organization in human and mouse tumours, identifying three regions: tumour body, proximal invasive front and distal invasive front. Invasive areas...
2.
Huerta-Lopez C, Clemente-Manteca A, Velazquez-Carreras D, Espinosa F, Sanchez J, Martinez-Del-Pozo A, et al.
Sci Adv
. 2024 Nov;
10(46):eadf9758.
PMID: 39546608
The mechanics of the extracellular matrix (ECM) determine cell activity and fate through mechanoresponsive proteins including Yes-associated protein 1 (YAP). Rigidity and viscous relaxation have emerged as the main mechanical...
3.
Uroz M, Stoddard A, Sutherland B, Courbot O, Oria R, Li L, et al.
Nat Cell Biol
. 2024 Oct;
26(12):2144-2153.
PMID: 39448802
In brain metastasis, cancer cells remain in close contact with the existing vasculature and can use vessels as migratory paths-a process known as vessel co-option. However, the mechanisms regulating this...
4.
Najibi A, Lane R, Sobral M, Bovone G, Kang S, Freedman B, et al.
Nat Biomed Eng
. 2024 May;
8(10):1226-1242.
PMID: 38710838
Following immunization, lymph nodes dynamically expand and contract. The mechanical and cellular changes enabling the early-stage expansion of lymph nodes have been characterized, yet the durability of such responses and...
5.
Sato N, Rosa V, Makhlouf A, Kretzmer H, Kumar A, Grosswendt S, et al.
Dev Cell
. 2024 Apr;
59(10):1252-1268.e13.
PMID: 38579720
The blueprint of the mammalian body plan is laid out during gastrulation, when a trilaminar embryo is formed. This process entails a burst of proliferation, the ingression of embryonic epiblast...
6.
Kechagia Z, Saez P, Gomez-Gonzalez M, Canales B, Viswanadha S, Zamarbide M, et al.
Nat Mater
. 2023 Sep;
22(11):1409-1420.
PMID: 37709930
The mechanical properties of the extracellular matrix dictate tissue behaviour. In epithelial tissues, laminin is a very abundant extracellular matrix component and a key supporting element. Here we show that...
7.
Han J, Bhatta R, Liu Y, Bo Y, Elosegui-Artola A, Wang H
Nat Commun
. 2023 Aug;
14(1):5049.
PMID: 37598185
Dendritic cell (DC) vaccine was among the first FDA-approved cancer immunotherapies, but has been limited by the modest cytotoxic T lymphocyte (CTL) response and therapeutic efficacy. Here we report a...
8.
Crosas-Molist E, Graziani V, Maiques O, Pandya P, Monger J, Samain R, et al.
Nat Commun
. 2023 May;
14(1):2740.
PMID: 37217519
Cell migration is crucial for cancer dissemination. We find that AMP-activated protein kinase (AMPK) controls cell migration by acting as an adhesion sensing molecular hub. In 3-dimensional matrices, fast-migrating amoeboid...
9.
Wu D, Diba M, Yang S, Freedman B, Elosegui-Artola A, Mooney D
Bioeng Transl Med
. 2023 May;
8(3):e10464.
PMID: 37206235
Multicellular spheroids made of stem cells can act as building blocks that fuse to capture complex aspects of native in vivo environments, but the effect of hydrogel viscoelasticity on cell...
10.
Elosegui-Artola A, Gupta A, Najibi A, Seo B, Garry R, Tringides C, et al.
Nat Mater
. 2022 Dec;
22(1):117-127.
PMID: 36456871
Biomolecular and physical cues of the extracellular matrix environment regulate collective cell dynamics and tissue patterning. Nonetheless, how the viscoelastic properties of the matrix regulate collective cell spatial and temporal...