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Ion Andreu

Explore the profile of Ion Andreu including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 960
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Recent Articles
1.
Granero-Moya I, Venturini V, Belthier G, Groenen B, Molina-Jordan M, Gonzalez-Martin M, et al.
J Cell Sci . 2024 Aug; 137(17). PMID: 39120491
Cells sense and respond to mechanical forces through mechanotransduction, which regulates processes in health and disease. In single adhesive cells, mechanotransduction involves the transmission of force from the extracellular matrix...
2.
Beedle A, Jaganathan A, Albajar-Sigales A, Yavitt F, Bera K, Andreu I, et al.
bioRxiv . 2023 Nov; PMID: 37986921
The cell nucleus is continuously exposed to external signals, of both chemical and mechanical nature. To ensure proper cellular response, cells need to regulate not only the transmission of these...
3.
Kechagia Z, Saez P, Gomez-Gonzalez M, Canales B, Viswanadha S, Zamarbide M, et al.
Nat Mater . 2023 Sep; 22(11):1409-1420. PMID: 37709930
The mechanical properties of the extracellular matrix dictate tissue behaviour. In epithelial tissues, laminin is a very abundant extracellular matrix component and a key supporting element. Here we show that...
4.
Abenza J, Rossetti L, Mouelhi M, Burgues J, Andreu I, Kennedy K, et al.
J Cell Biol . 2023 Jun; 222(9). PMID: 37378613
Autonomous circadian clocks exist in nearly every mammalian cell type. These cellular clocks are subjected to a multilayered regulation sensitive to the mechanochemical cell microenvironment. Whereas the biochemical signaling that...
5.
Andreu I, Granero-Moya I, Garcia-Manyes S, Roca-Cusachs P
APL Bioeng . 2022 Jul; 6(2):020901. PMID: 35783457
Cell nuclei are submitted to mechanical forces, which in turn affect nuclear and cell functions. Recent evidence shows that a crucial mechanically regulated nuclear function is nucleocytoplasmic transport, mediated by...
6.
Andreu I, Granero-Moya I, Chahare N, Clein K, Molina-Jordan M, Beedle A, et al.
Nat Cell Biol . 2022 Jun; 24(6):896-905. PMID: 35681009
Mechanical force controls fundamental cellular processes in health and disease, and increasing evidence shows that the nucleus both experiences and senses applied forces. Such forces can lead to the nuclear...
7.
Andreu I, Falcones B, Hurst S, Chahare N, Quiroga X, Le Roux A, et al.
Nat Commun . 2021 Jul; 12(1):4229. PMID: 34244477
Cell response to force regulates essential processes in health and disease. However, the fundamental mechanical variables that cells sense and respond to remain unclear. Here we show that the rate...
8.
Guixe-Muntet S, Ortega-Ribera M, Wang C, Selicean S, Andreu I, Kechagia J, et al.
JHEP Rep . 2020 Sep; 2(5):100145. PMID: 32939447
Background & Aims: Liver stiffness is increased in advanced chronic liver disease (ACLD) and accurately predicts prognosis in this population. Recent data suggest that extracellular matrix stiffness may modulate the...
9.
Lerche M, Elosegui-Artola A, Kechagia J, Guzman C, Georgiadou M, Andreu I, et al.
iScience . 2020 Sep; 23(9):101507. PMID: 32896770
[This corrects the article DOI: 10.1016/j.isci.2020.100907.].
10.
Lerche M, Elosegui-Artola A, Kechagia J, Guzman C, Georgiadou M, Andreu I, et al.
iScience . 2020 Feb; 23(3):100907. PMID: 32106057
The link between integrin activity regulation and cellular mechanosensing of tissue rigidity, especially on different extracellular matrix ligands, remains poorly understood. Here, we find that primary mouse mammary gland stromal...