Albert S Agustinus
Overview
Explore the profile of Albert S Agustinus including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
7
Citations
150
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Di Bona M, Chen Y, Agustinus A, Mazzagatti A, Duran M, Deyell M, et al.
Science
. 2024 Aug;
385(6712):eadj8691.
PMID: 39208110
Chromosome-containing micronuclei are a hallmark of aggressive cancers. Micronuclei frequently undergo irreversible collapse, exposing their enclosed chromatin to the cytosol. Micronuclear rupture catalyzes chromosomal rearrangements, epigenetic abnormalities, and inflammation, yet...
2.
Chen X, Agustinus A, Li J, DiBona M, Bakhoum S
Nat Rev Genet
. 2024 Jul;
26(1):31-46.
PMID: 39075192
Chromosomal instability (CIN) refers to an increased propensity of cells to acquire structural and numerical chromosomal abnormalities during cell division, which contributes to tumour genetic heterogeneity. CIN has long been...
3.
Agustinus A, David Y
Nat Struct Mol Biol
. 2024 Jan;
31(1):8-10.
PMID: 38253662
No abstract available.
4.
Agustinus A, Al-Rawi D, Dameracharla B, Raviram R, Jones B, Stransky S, et al.
Nature
. 2023 Jun;
619(7968):176-183.
PMID: 37286593
Chromosomal instability (CIN) and epigenetic alterations are characteristics of advanced and metastatic cancers, but whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their...
5.
Agustinus A, Bakhoum S
Methods Cell Biol
. 2022 Sep;
172:51-66.
PMID: 36064226
Micronuclei are common byproducts of chromosomally unstable cancer cells during their division. Micronuclei play an important role in cancer metastasis as well as introducing chromosomal abnormalities into the primary nucleus...
6.
Zheng Q, Omans N, Leicher R, Osunsade A, Agustinus A, Finkin-Groner E, et al.
Nat Commun
. 2019 Mar;
10(1):1289.
PMID: 30894531
Cellular proteins continuously undergo non-enzymatic covalent modifications (NECMs) that accumulate under normal physiological conditions and are stimulated by changes in the cellular microenvironment. Glycation, the hallmark of diabetes, is a...
7.
Yin L, Agustinus A, Yuvienco C, Minashima T, Schnabel N, Kirsch T, et al.
Biomacromolecules
. 2018 Mar;
19(5):1614-1624.
PMID: 29601728
Osteoarthritis (OA) results from degenerative and abnormal function of joints, with localized biochemistry playing a critical role in its onset and progression. As high levels of all- trans retinoic acid...