Lorenzo Scipioni
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Explore the profile of Lorenzo Scipioni including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
304
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Recent Articles
1.
Tedeschi G, Navarro M, Scipioni L, Sondhi T, Prescher J, Digman M
Chem Biomed Imaging
. 2024 Nov;
2(11):765-774.
PMID: 39610466
Macrophages exhibit a spectrum of behaviors upon activation and are generally classified as one of two types: inflammatory (M1) or anti-inflammatory (M2). Tracking these phenotypes in living cells can provide...
2.
Torrey Z, Halbers L, Scipioni L, Tedeschi G, Digman M, Prescher J
RSC Chem Biol
. 2024 Sep;
PMID: 39308479
Bioluminescence is a powerful method for imaging , but applications at the microscale are far from routine. This is due, in part, to a lack of versatile tools for visualizing...
3.
Di Bona M, Chen Y, Agustinus A, Mazzagatti A, Duran M, Deyell M, et al.
Science
. 2024 Aug;
385(6712):eadj8691.
PMID: 39208110
Chromosome-containing micronuclei are a hallmark of aggressive cancers. Micronuclei frequently undergo irreversible collapse, exposing their enclosed chromatin to the cytosol. Micronuclear rupture catalyzes chromosomal rearrangements, epigenetic abnormalities, and inflammation, yet...
4.
Park S, Wang X, Mo Y, Zhang S, Li X, Fong K, et al.
J Mater Chem B
. 2024 Aug;
12(34):8335-8348.
PMID: 39105364
Understanding protein-protein interactions (PPIs) through proximity labeling has revolutionized our comprehension of cellular mechanisms and pathology. Various proximity labeling techniques, such as HRP, APEX, BioID, TurboID, and μMap, have been...
5.
Carretta A, Moscardini A, Signore G, Debellis D, Catalano F, Marotta R, et al.
Mol Ther Oncol
. 2024 Jul;
32(3):200836.
PMID: 39050990
The successful trajectory of liposome-encapsulated doxorubicin (e.g., Doxil, which has been approved by the U.S. Food and Drug Administration) as an anticancer nanodrug in clinical applications is contradicted by cell...
6.
Sakthivel P, Scipioni L, Karam J, Keulen Z, Blurton-Jones M, Gratton E, et al.
J Neurochem
. 2024 Jul;
168(9):3095-3107.
PMID: 39018376
Microglia, the immune cells of the central nervous system, are dynamic and heterogenous cells. While single cell RNA sequencing has become the conventional methodology for evaluating microglial state, transcriptomics do...
7.
Tedeschi G, Navarro M, Scipioni L, Sondhi T, Prescher J, Digman M
bioRxiv
. 2024 Jun;
PMID: 38915606
Macrophages exhibit a spectrum of behaviors upon activation and are generally classified as one of two types: inflammatory (M1) or anti-inflammatory (M2). Tracking these phenotypes in living cells can provide...
8.
Tedeschi G, Palomba F, Scipioni L, Digman M
bioRxiv
. 2024 Jun;
PMID: 38915530
We implemented a multimodal set of functional imaging techniques optimized for deep-tissue imaging to investigate how cancer cells invade surrounding tissues and how their physiological properties change in the process....
9.
Fazel M, Jazani S, Scipioni L, Vallmitjana A, Zhu S, Gratton E, et al.
ACS Photonics
. 2024 Feb;
10(10):3558-3569.
PMID: 38406580
Fluorescence lifetime imaging microscopy (FLIM) has become a standard tool in the quantitative characterization of subcellular environments. However, quantitative FLIM analyses face several challenges. First, spatial correlations between pixels are...
10.
Park S, Wang X, Li X, Huang X, Fong K, Yu C, et al.
bioRxiv
. 2023 Nov;
PMID: 38014020
Elucidating the spatial relationships within the protein interactome is pivotal to understanding the organization and regulation of protein-protein interactions. However, capturing the 3D architecture of the interactome presents a dual...