Alban Ordureau
Overview
Explore the profile of Alban Ordureau including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
56
Citations
4997
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pham B, Yi S, Ordureau A, An H
Cell Rep
. 2025 Jan;
44(1):115179.
PMID: 39808525
One critical aspect of cell proliferation is increased nucleotide synthesis, including pyrimidines. Pyrimidines are synthesized through de novo and salvage pathways. Prior studies established that the mammalian target of rapamycin...
2.
Di Bona M, Chen Y, Agustinus A, Mazzagatti A, Duran M, Deyell M, et al.
Science
. 2024 Aug;
385(6712):eadj8691.
PMID: 39208110
Chromosome-containing micronuclei are a hallmark of aggressive cancers. Micronuclei frequently undergo irreversible collapse, exposing their enclosed chromatin to the cytosol. Micronuclear rupture catalyzes chromosomal rearrangements, epigenetic abnormalities, and inflammation, yet...
3.
Zenge C, Ordureau A
Trends Biochem Sci
. 2024 Jul;
49(10):875-887.
PMID: 38972780
Neuronal ubiquitin balance impacts the fate of countless cellular proteins, and its disruption is associated with various neurological disorders. The ubiquitin system is critical for proper neuronal cell state transitions...
4.
Sinha N, McKenney C, Yeow Z, Li J, Nam K, Yaron-Barir T, et al.
Cell
. 2024 Jun;
187(14):3652-3670.e40.
PMID: 38843833
While ultraviolet (UV) radiation damages DNA, eliciting the DNA damage response (DDR), it also damages RNA, triggering transcriptome-wide ribosomal collisions and eliciting a ribotoxic stress response (RSR). However, the relative...
5.
Yi S, Sepic S, Schulman B, Ordureau A, An H
Mol Cell
. 2024 May;
84(11):2166-2184.e9.
PMID: 38788716
Mammalian target of rapamycin (mTOR) senses changes in nutrient status and stimulates the autophagic process to recycle amino acids. However, the impact of nutrient stress on protein degradation beyond autophagic...
6.
Hertz N, Chin R, Rakhit R, Ditsworth D, Wang C, Bartholomeus J, et al.
Res Sq
. 2024 May;
PMID: 38765977
PINK1 loss-of-function mutations and exposure to mitochondrial toxins are causative for Parkinson's disease (PD) and Parkinsonism, respectively. We demonstrate that pathological α-synuclein deposition, the hallmark pathology of idiopathic PD, induces...
7.
Nam K, Ordureau A
Biochem Soc Trans
. 2024 Mar;
52(2):581-592.
PMID: 38488108
Even though neurons are post-mitotic cells, they still engage in protein synthesis to uphold their cellular content balance, including for organelles, such as the endoplasmic reticulum or mitochondria. Additionally, they...
8.
DaRosa P, Penchev I, Gumbin S, Scavone F, Wachalska M, Paulo J, et al.
Nature
. 2024 Feb;
627(8003):445-452.
PMID: 38383785
Reversible modification of target proteins by ubiquitin and ubiquitin-like proteins (UBLs) is widely used by eukaryotic cells to control protein fate and cell behaviour. UFM1 is a UBL that predominantly...
9.
Goldsmith J, Ordureau A, Harper J, Holzbaur E
Neuron
. 2024 Feb;
112(3):520.
PMID: 38330901
No abstract available.
10.
Watts M, Giadone R, Ordureau A, Holton K, Harper J, Rubin L
Front Cell Neurosci
. 2024 Feb;
17:1327361.
PMID: 38314348
Amyotrophic lateral sclerosis (ALS) is a degenerative motor neuron (MN) disease with severely limited treatment options. Identification of effective treatments has been limited in part by the lack of predictive...