Aisling Dunne
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Explore the profile of Aisling Dunne including associated specialties, affiliations and a list of published articles.
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56
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2757
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Recent Articles
21.
McCarthy G, Dunne A
Nat Rev Rheumatol
. 2018 Sep;
14(10):592-602.
PMID: 30190520
The most common types of calcium-containing crystals that are associated with joint and periarticular disorders are calcium pyrophosphate dihydrate (CPP) and basic calcium phosphate (BCP) crystals. Several diverse but difficult-to-treat...
22.
Campbell N, Fitzgerald H, Malara A, Hambly R, Sweeney C, Kirby B, et al.
Sci Rep
. 2018 Jul;
8(1):10287.
PMID: 29980703
Psoriasis is a chronic autoimmune disease mediated by dysregulated immune responses in dendritic cells (DC) and T cells. The stress-response enzyme heme oxygenase-1 (HO-1) has been described as protective in...
23.
Mahon O, Dunne A
Front Immunol
. 2018 Jun;
9:1145.
PMID: 29892292
It is now well established that intra-articular deposition of endogenous particulates, such as osteoarthritis-associated basic calcium phosphate crystals, gout-associated monosodium urate crystals, and calcium deposition disease-associated calcium pyrophosphate crystals, contributes...
24.
Mahon O, OHanlon S, Cunningham C, McCarthy G, Hobbs C, Nicolosi V, et al.
Acta Biomater
. 2017 Nov;
65:426-435.
PMID: 29104084
Statement Of Significance: It is now well established that wear-debris particles from implanted materials drive deleterious inflammatory responses which can eventually lead to implant loosening. In this study, we provide...
25.
Corr E, Cunningham C, Helbert L, McCarthy G, Dunne A
Arthritis Res Ther
. 2017 Feb;
19(1):23.
PMID: 28173838
Background: Osteoarthritis (OA) is a chronic debilitating joint disorder of particularly high prevalence in the elderly population. Intra-articular basic calcium phosphate (BCP) crystals are present in the majority of OA...
26.
Gray P, Dunne A, Brikos C, Jefferies C, Doyle S, O Neill L
J Biol Chem
. 2016 Dec;
291(50):26240.
PMID: 27941071
No abstract available.
27.
IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal)
Dunne A, Carpenter S, Brikos C, Gray P, Strelow A, Wesche H, et al.
J Biol Chem
. 2016 Nov;
291(47):24802.
PMID: 27864528
No abstract available.
28.
Basdeo S, Campbell N, Sullivan L, Flood B, Creagh E, Mantle T, et al.
Transl Res
. 2016 Aug;
178:81-94.e2.
PMID: 27497182
The main limitation to successful transplantation is the antigraft response developed by the recipient immune system, and the adverse side effects of immunosuppressive agents which are associated with significant toxicity...
29.
Corr E, Cunningham C, Dunne A
Atherosclerosis
. 2016 Jun;
251:197-205.
PMID: 27356299
Background And Aims: Cholesterol crystals are a key component of atherosclerotic lesions where they promote pro-inflammatory cytokine production and plaque destabilization. Antagonists of inflammatory mediators and agents that dissolve or...
30.
Cunningham C, Corr E, Cox D, Dunne A
Methods Mol Biol
. 2015 Mar;
1292:105-13.
PMID: 25804751
Inflammasomes are large multiprotein complexes that assemble in response to cellular stress and infection. NOD-like receptor-related proteins (NLRPs) are essential components of these complexes and are activated by exogenous and...