Clare C Cunningham
Overview
Explore the profile of Clare C Cunningham including associated specialties, affiliations and a list of published articles.
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12
Citations
240
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Recent Articles
1.
Barker B, Hanlon M, Marzaioli V, Smith C, Cunningham C, Fletcher J, et al.
Front Med (Lausanne)
. 2023 Feb;
10:1029021.
PMID: 36817783
Objectives: The mammalian target of Rapamycin (mTOR) is a metabolic master regulator of both innate and adaptive immunity; however, its exact role in stromal cell biology is unknown. In this...
2.
Cunningham C, Wade S, Floudas A, Orr C, McGarry T, Wade S, et al.
Front Immunol
. 2021 Mar;
12:633201.
PMID: 33746971
Background: MicroRNAs (miRNAs) are small non-coding RNAs which have been implicated as potential biomarkers or therapeutic targets in autoimmune diseases. This study examines circulatory miRNAs in RA patients and further...
3.
McGarry T, Hanlon M, Marzaioli V, Cunningham C, Krishna V, Murray K, et al.
Clin Transl Immunology
. 2021 Jan;
10(1):e1237.
PMID: 33510894
Introduction: This study investigates the metabolic activity of circulating monocytes and their impact on pro-inflammatory responses in RA and explores whether this phenotype is already primed for inflammation before clinical...
4.
Campbell N, Williams D, Fitzgerald H, Barry P, Cunningham C, Nolan D, et al.
Front Immunol
. 2019 Oct;
10:2137.
PMID: 31572363
African trypanosomes, such as (), are protozoan parasites of the mammalian vasculature and central nervous system that are best known for causing fatal human sleeping sickness. As exclusively extracellular parasites,...
5.
Hanlon M, Rakovich T, Cunningham C, Ansboro S, Veale D, Fearon U, et al.
Front Immunol
. 2019 Sep;
10:2056.
PMID: 31555281
Oncostatin M (OSM), a pleiotropic cytokine and a member of the gp130/IL-6 cytokine family, has been implicated in the pathogenesis of autoimmune diseases. Here we investigate the mechanisms by which...
6.
Wade S, Ohnesorge N, McLoughlin H, Biniecka M, Carter S, Trenkman M, et al.
EBioMedicine
. 2019 Aug;
47:402-413.
PMID: 31466915
Background: Although neoangiogenesis is a hallmark of chronic inflammatory diseases such as inflammatory arthritis and many cancers, therapeutic agents targeting the vasculature remain elusive. Here we identified miR-125a as an...
7.
Silveira A, Mahon O, Cunningham C, Corr E, Mendonca R, Saad S, et al.
J Leukoc Biol
. 2019 May;
106(1):35-43.
PMID: 31091351
Intravascular hemolysis, in addition to reducing red cell counts, incurs extensive vascular inflammation and oxidative stress. One product of hemolysis, heme, is a potent danger associated molecular pattern (DAMP), activating...
8.
Mahon O, OHanlon S, Cunningham C, McCarthy G, Hobbs C, Nicolosi V, et al.
Acta Biomater
. 2017 Nov;
65:426-435.
PMID: 29104084
Statement Of Significance: It is now well established that wear-debris particles from implanted materials drive deleterious inflammatory responses which can eventually lead to implant loosening. In this study, we provide...
9.
Corr E, Cunningham C, Helbert L, McCarthy G, Dunne A
Arthritis Res Ther
. 2017 Feb;
19(1):23.
PMID: 28173838
Background: Osteoarthritis (OA) is a chronic debilitating joint disorder of particularly high prevalence in the elderly population. Intra-articular basic calcium phosphate (BCP) crystals are present in the majority of OA...
10.
Corr E, Cunningham C, Dunne A
Atherosclerosis
. 2016 Jun;
251:197-205.
PMID: 27356299
Background And Aims: Cholesterol crystals are a key component of atherosclerotic lesions where they promote pro-inflammatory cytokine production and plaque destabilization. Antagonists of inflammatory mediators and agents that dissolve or...