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Ahmed A Elbatrawy

Explore the profile of Ahmed A Elbatrawy including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 37
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Recent Articles
1.
Elbatrawy A, Ademoye T, Alnakhala H, Tripathi A, Zhu X, Plascencia-Villa G, et al.
ACS Omega . 2025 Mar; 10(7):6721-6734. PMID: 40028124
Alzheimer's (AD) and Parkinson's (PD) disease are neurodegenerative disorders that are considered to be a significant global health challenge due to their increasing prevalence and profound impact on both individuals...
2.
Elbatrawy A, Ademoye T, Alnakhala H, Tripathi A, Plascencia-Villa G, Zhu X, et al.
Bioorg Med Chem . 2024 Nov; 116:117990. PMID: 39550891
Tau and α-synuclein (α-syn) are prone-to-aggregate proteins that can be responsible for pathological lesions found in the brains of Alzheimer's disease (AD), Lewy body dementia (LBD), and Parkinson's disease (PD)...
3.
Elbatrawy A, Ademoye T, Alnakhala H, Tripathi A, Zami A, Ostafe R, et al.
Bioorg Med Chem . 2024 Feb; 100:117613. PMID: 38330847
Tau and α-synuclein aggregates are the main histopathological hallmarks present in Alzheimer's disease (AD), Parkinson's disease (PD), and other neurodegenerative disorders. Intraneuronal hyperphosphorylated tau accumulation is significantly connected to the...
4.
Ramirez E, Ganegamage S, Elbatrawy A, Alnakhala H, Shimanaka K, Tripathi A, et al.
ACS Omega . 2023 Jun; 8(22):20102-20115. PMID: 37305264
Protein misfolding results in a plethora of known diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, transthyretin-related amyloidosis, type 2 diabetes, Lewy body dementia, and spongiform encephalopathy. To provide...
5.
Elbatrawy A, Hyeon S, Yue N, Osman E, Choi S, Lim S, et al.
ACS Sens . 2021 Jun; 6(6):2281-2289. PMID: 34115933
Tau aggregation is believed to have a strong association with the level of cognitive deficits in Alzheimer's disease (AD). Thus, optical brain imaging of tau aggregates has recently gained substantial...
6.
Elbatrawy A, Lee D, Lee S, Jeon H, Lee S, Kang K, et al.
J Mater Chem B . 2021 Jun; 9(24):4857-4862. PMID: 34076031
Fluorescent imaging agents with biocompatibility and high sensitivity are urgently required for the accurate detection of sentinel lymph nodes (SLNs). Herein, we report the design of a novel quinoline-based fluorescent...
7.
Elbatrawy A, Kim E, Nam G
ChemMedChem . 2020 Jun; 15(14):1244-1257. PMID: 32496638
O-GlcNAcylation is the dynamic and ubiquitous post-translational glycosylation of nucleocytoplasmic proteins on serine/threonine residues; it is implicated in regulation of the cell cycle. This protein modification is mainly governed by...
8.
El-Moghazy S, George R, Osman E, Elbatrawy A, Kissova M, Colombo A, et al.
Eur J Med Chem . 2016 Jul; 123:1-13. PMID: 27474918
Some novel 6-substituted pyrazolo[3,4-d]pyrimidines 4, 5, 6a-d, 7a-c, 8 and pyrazolo[4,3-e][1,2,4]triazolo[4,3-a]pyrimidines 9a-c, 10a-c, 11, 12a,b, 13a-c and 14 were synthesized and characterized by spectral and elemental analyses. They were screened...