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Adam A Stromstedt

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Articles 33
Citations 478
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Recent Articles
1.
Jacobsson E, Stromstedt A, Andersson H, Avila C, Goransson U
Toxins (Basel) . 2024 May; 16(5). PMID: 38787061
Peptide toxins from marine invertebrates have found use as drugs and in biotechnological applications. Many marine habitats, however, remain underexplored for natural products, and the Southern Ocean is among them....
2.
Muhammad T, Stromstedt A, Gunasekera S, Goransson U
Biomedicines . 2023 Feb; 11(2). PMID: 36831040
Is it possible to enhance structural stability and biological activity of KR-12, a truncated antimicrobial peptide derived from the human host defense peptide LL-37? Based on the mapping of essential...
3.
Rajendran S, Slazak B, Mohotti S, Muhammad T, Stromstedt A, Kapusta M, et al.
J Nat Prod . 2022 Dec; 86(1):52-65. PMID: 36525646
Cyclotides are an intriguing class of structurally stable circular miniproteins of plant origin with numerous potential pharmaceutical and agricultural applications. To investigate the occurrence of cyclotides in Sri Lankan flora,...
4.
White J, Muhammad T, Alsheim E, Mohanty S, Blasi-Romero A, Gunasekera S, et al.
Cell Mol Life Sci . 2022 Jul; 79(8):411. PMID: 35821354
The increasing antibiotic resistance among uropathogenic bacteria warrants alternative therapeutic strategies. We demonstrate the potential of the synthetic peptide CD4-PP, designed by dimerization and backbone cyclization of the shortest antimicrobial...
5.
Rajendran S, Slazak B, Mohotti S, Stromstedt A, Goransson U, Hettiarachchi C, et al.
Phytochemistry . 2021 May; 187:112749. PMID: 33932786
Cyclotides are an extremely stable class of peptides, ubiquitously distributed in Violaceae. The aim of the present study was to investigate the presence of cyclotides in Sri Lankan Violaceae plants,...
6.
Nord C, Bjerketorp J, Levenfors J, Cao S, Stromstedt A, Guss B, et al.
ACS Chem Biol . 2020 Oct; 15(11):2937-2944. PMID: 33054165
strain UP508 was isolated from a soil sample using a mixture of ampicillin, kanamycin, and nalidixic acid for selection. UP508 was found to produce >30 unknown antibacterial peptides, of which...
7.
Gunasekera S, Muhammad T, Stromstedt A, Rosengren K, Goransson U
Front Microbiol . 2020 Mar; 11:168. PMID: 32153522
Can antimicrobial activity and peptide stability of alpha-helical peptides be increased by making them into dimers and macrocycles? Here, we explore that concept by using KR-12 as the starting point...
8.
Haffner S, Nystrom L, Stromstedt A, Li L, van der Plas M, Malmsten M
J Colloid Interface Sci . 2019 Dec; 562:71-80. PMID: 31837621
Effects of size and charge of anionic nanoclays on their interactions with bacteria-mimicking lipid membranes, bacterial lipopolysaccharide (LPS), and Gram-negative bacteria were investigated using ellipsometry, dynamic light scattering, ζ-potential measurements,...
9.
Ismail N, Odendaal C, Serem J, Stromstedt A, Bester M, Sayed Y, et al.
J Pept Sci . 2019 Nov; 25(12):e3223. PMID: 31713951
Previously Os, a 22 amino acid sequence of a defensin from the soft tick Ornithodoros savignyi, was found to kill Gram-positive and Gram-negative bacteria at low micromolar concentrations. In this...
10.
Mohotti S, Rajendran S, Muhammad T, Stromstedt A, Adhikari A, Burman R, et al.
J Ethnopharmacol . 2019 Aug; 246:112158. PMID: 31421182
Ethnopharmacological Relevance: Sri Lanka is known to have very diverse flora. Many of these species are used for plant-based remedies, which form the integral part of two Sri Lankan systems...