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Adam A Stromstedt

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Articles 33
Citations 478
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Recent Articles
11.
Haffner S, Nystrom L, Browning K, Nielsen H, Stromstedt A, van der Plas M, et al.
ACS Appl Mater Interfaces . 2019 Apr; 11(17):15389-15400. PMID: 30951282
The antimicrobial effects of Laponite nanoparticles with or without loading of the antimicrobial peptide LL-37 was investigated along with their membrane interactions. The study combines data from ellipsometry, circular dichroism,...
12.
Nystrom L, Al-Rammahi N, Haffner S, Stromstedt A, Browning K, Malmsten M
Biomacromolecules . 2018 Nov; 19(12):4691-4702. PMID: 30427659
Herein, we report on the formation of cross-linked antimicrobial peptide-loaded microgel multilayers. Poly(ethyl acrylate- co-methacrylic acid) microgels were synthesized and functionalized with biotin to enable the formation of microgel multilayers...
13.
Slazak B, Kapusta M, Stromstedt A, Slomka A, Krychowiak M, Shariatgorji M, et al.
Front Plant Sci . 2018 Sep; 9:1296. PMID: 30254654
Cyclotides are cyclic plant polypeptides of 27-37 amino acid residues. They have been extensively studied in bioengineering and drug development contexts. However, less is known about the relevance of cyclotides...
14.
Nystrom L, Stromstedt A, Schmidtchen A, Malmsten M
Biomacromolecules . 2018 Jul; 19(8):3456-3466. PMID: 29976055
Here we report on covalently immobilized poly(ethyl acrylate- co-methacrylic acid) microgels loaded with the host defense peptide KYE28 (KYEITTIHNLFRKLTHRLFRRNFGYTLR), which is derived from human heparin cofactor II, as well as...
15.
Abdillahi S, Maass T, Kasetty G, Stromstedt A, Baumgarten M, Tati R, et al.
J Immunol . 2018 Jun; 201(3):1007-1020. PMID: 29925677
Collagen VI is a ubiquitous extracellular matrix component that forms extensive microfibrillar networks in most connective tissues. In this study, we describe for the first time, to our knowledge, that...
16.
Forde E, Shafiy G, Fitzgerald-Hughes D, Stromstedt A, Devocelle M
J Pept Sci . 2018 May; 24(7):e3086. PMID: 29799150
Antimicrobial peptides (AMPs) are promising broad-spectrum antibiotic candidates in the wake of multi-drug resistant pathogens. Their clinical use still requires a solution based on lead optimisation and/or formulation to overcome...
17.
Gunasekera S, Muhammad T, Stromstedt A, Rosengren K, Goransson U
Chembiochem . 2018 Feb; 19(9):931-939. PMID: 29430821
The human host defence peptide LL-37 is a broad-spectrum antibiotic with immunomodulatory functions. Residues 18-29 in LL-37 have previously been identified as a minimal peptide (KR-12) that retains antibacterial activity...
18.
Stromstedt A, Park S, Burman R, Goransson U
Biochim Biophys Acta Biomembr . 2017 Jul; 1859(10):1986-2000. PMID: 28669767
Cyclotides are a family of plant peptides characterized by a cystine knot embedded in a macrocyclic backbone. They bind to and disrupt phospholipid membranes, which explain their lytic activity on...
19.
Raschig J, Mailander-Sanchez D, Berscheid A, Berger J, Stromstedt A, Courth L, et al.
PLoS Pathog . 2017 Mar; 13(3):e1006261. PMID: 28323883
Ever since the discovery of endogenous host defense antimicrobial peptides it has been discussed how these evolutionary conserved molecules avoid to induce resistance and to remain effective. Human ß-defensin 1...
20.
Kirkpatrick C, Broberg C, McCool E, Lee W, Chao A, McConnell E, et al.
Anal Chem . 2016 Dec; 89(2):1194-1201. PMID: 27991763
The recent increase in extensively drug-resistant bacterial pathogens and the associated increase of morbidity and mortality demonstrate the immediate need for new antibiotic backbones with novel mechanisms of action. Here,...