Abraham Acevedo-Arozena
Overview
Explore the profile of Abraham Acevedo-Arozena including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
4496
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Recent Articles
1.
Moreno-Martinez L, Gaja-Capdevila N, Mosqueira-Martin L, Herrando-Grabulosa M, Rodriguez-Gomez L, Gonzalez-Imaz K, et al.
Br J Pharmacol
. 2025 Feb;
PMID: 39947630
Background And Purpose: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with limited treatment options. ALS pathogenesis involves intricate processes within motor neurons, characterized by dysregulated Ca influx and...
2.
Godoy-Corchuelo J, Ali Z, Brito Armas J, Martins-Bach A, Garcia-Toledo I, Fernandez-Beltran L, et al.
Neurobiol Dis
. 2024 Oct;
202:106708.
PMID: 39462744
No abstract available.
3.
Godoy-Corchuelo J, Ali Z, Brito Armas J, Martins-Bach A, Garcia-Toledo I, Fernandez-Beltran L, et al.
Neurobiol Dis
. 2024 Feb;
193:106437.
PMID: 38367882
TDP-43 pathology is found in several neurodegenerative disorders, collectively referred to as "TDP-43 proteinopathies". Aggregates of TDP-43 are present in the brains and spinal cords of >97% of amyotrophic lateral...
4.
Estevez-Silva H, Cuesto G, Romero N, Brito-Armas J, Acevedo-Arozena A, Acebes A, et al.
Neurotherapeutics
. 2022 Aug;
19(5):1566-1587.
PMID: 35917088
Sigma-1 receptor agonists have recently gained a great deal of interest due to their anti-amnesic, neuroprotective, and neurorestorative properties. Compounds such as PRE-084 or pridopidine (ACR16) are being studied as...
5.
Devoy A, Price G, De Giorgio F, Bunton-Stasyshyn R, Thompson D, Gasco S, et al.
iScience
. 2022 Mar;
25(4):103999.
PMID: 35296030
[This corrects the article DOI: 10.1016/j.isci.2021.103463.].
6.
Devoy A, Price G, De Giorgio F, Bunton-Stasyshyn R, Thompson D, Gasco S, et al.
iScience
. 2022 Jan;
24(12):103463.
PMID: 34988393
Amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) is a fatal neurodegenerative disorder, and continued innovation is needed for improved understanding and for developing therapeutics. We have created next-generation knockin mouse models, by...
7.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
8.
Rodriguez-Rodriguez A, Donate-Correa J, Rovira J, Cuesto G, Luis-Ravelo D, Fernandes M, et al.
Am J Transplant
. 2019 Jun;
19(12):3240-3249.
PMID: 31152486
The mechanisms of tacrolimus-induced β cell toxicity are unknown. Tacrolimus (TAC) and rapamycin (Rapa) both bind to FK506-binding protein 12 (FKBP12). Also, both molecular structures are similar. Because of this...
9.
Tan S, Kermasson L, Hoslin A, Jaako P, Faille A, Acevedo-Arozena A, et al.
Blood
. 2019 Jun;
134(3):277-290.
PMID: 31151987
Shwachman-Diamond syndrome (SDS) is a recessive disorder typified by bone marrow failure and predisposition to hematological malignancies. SDS is predominantly caused by deficiency of the allosteric regulator Shwachman-Bodian-Diamond syndrome that...
10.
Stewart M, Lau P, Banks G, Bains R, Castroflorio E, Oliver P, et al.
Dis Model Mech
. 2019 Jan;
12(2).
PMID: 30692144
Loss-of-function mutations in a human AMPA receptor-associated protein, ferric chelate reductase 1-like (FRRS1L), are associated with a devastating neurological condition incorporating choreoathetosis, cognitive deficits and epileptic encephalopathies. Furthermore, evidence from...