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Abdullah Alsuliman

Explore the profile of Abdullah Alsuliman including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 782
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Recent Articles
1.
Janssen E, Alosaimi M, AlAzami A, Alsuliman A, Alaiya A, Al-Saud B, et al.
J Allergy Clin Immunol . 2022 Oct; 151(2):572-578.e1. PMID: 36243222
Background: The type II transmembrane protein fibrinogen-like protein 2 (FGL2) plays critical roles in hemostasis and immune regulation. The C-terminal immunoregulatory domain of FGL2 can be secreted and is a...
2.
Shaim H, Shanley M, Basar R, Daher M, Gumin J, Zamler D, et al.
J Clin Invest . 2021 Jun; 131(14). PMID: 34138753
Glioblastoma multiforme (GBM), the most aggressive brain cancer, recurs because glioblastoma stem cells (GSCs) are resistant to all standard therapies. We showed that GSCs, but not normal astrocytes, are sensitive...
3.
Basar R, Daher M, Uprety N, Gokdemir E, Alsuliman A, Ensley E, et al.
Blood Adv . 2020 Jul; 4(14):3357-3367. PMID: 32717029
Virus-specific T cells have proven highly effective for the treatment of severe and drug-refractory infections after hematopoietic stem cell transplant (HSCT). However, the efficacy of these cells is hindered by...
4.
Weathers S, Penas-Prado M, Pei B, Ling X, Kassab C, Banerjee P, et al.
Clin Cancer Res . 2020 Apr; 26(14):3565-3577. PMID: 32299815
Purpose: Cytomegalovirus (CMV) antigens occur in glioblastoma but not in normal brains, making them desirable immunologic targets. Patients And Methods: Highly functional autologous polyclonal CMV pp65-specific T cells from patients...
5.
Khoder A, Alsuliman A, Basar R, Sobieski C, Kondo K, Alousi A, et al.
Front Immunol . 2018 Jan; 8:1937. PMID: 29375566
Chronic graft-versus-host disease (cGvHD) remains a major complication of allogeneic hematopoietic stem cell transplantation (HSCT). A number of studies support a role for B cells in the pathogenesis of cGvHD....
6.
Alsuliman A, Muftuoglu M, Khoder A, Ahn Y, Basar R, Verneris M, et al.
Blood . 2016 Nov; 129(6):740-758. PMID: 27821506
The establishment of long-lived pathogen-specific T cells is a fundamental property of the adaptive immune response. However, the mechanisms underlying long-term persistence of antigen-specific CD4 T cells are not well-defined....
7.
Alsuliman A, Appel S, Beers D, Basar R, Shaim H, Kaur I, et al.
Cytotherapy . 2016 Aug; 18(10):1312-24. PMID: 27497700
Regulatory T cells (Tregs) play a fundamental role in the maintenance of self-tolerance and immune homeostasis. Defects in Treg function and/or frequencies have been reported in multiple disease models. Amyotrophic...
8.
Sarvaria A, Basar R, Mehta R, Shaim H, Muftuoglu M, Khoder A, et al.
Blood . 2016 Jul; 128(10):1346-61. PMID: 27439912
Cord blood (CB) offers a number of advantages over other sources of hematopoietic stem cells, including a lower rate of chronic graft-versus-host disease (cGVHD) in the presence of increased HLA...
9.
Sekine T, Marin D, Cao K, Li L, Mehta P, Shaim H, et al.
Blood . 2016 Jun; 128(2):297-312. PMID: 27247137
The ability of cord blood transplantation (CBT) to prevent relapse depends partly on donor natural killer (NK) cell alloreactivity. NK effector function depends on specific killer-cell immunoglobulin-like receptors (KIR) and...
10.
Alsuliman A, Colak D, Al-Harazi O, Fitwi H, Tulbah A, Al-Tweigeri T, et al.
Mol Cancer . 2015 Aug; 14:149. PMID: 26245467
Background: The T-cell inhibitory molecule PD-L1 (B7-H1, CD274) is expressed on tumor cells of a subset of breast cancer patients. However, the mechanism that regulates PD-L1 expression in this group...