Abdelouahid Maghnouj
Overview
Explore the profile of Abdelouahid Maghnouj including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
846
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0
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Recent Articles
1.
Schuler I, Schuler M, Frick T, Jimenez D, Maghnouj A, Hahn S, et al.
Analyst
. 2024 Mar;
149(7):2004-2015.
PMID: 38426854
HER2 is a crucial therapeutic target in breast cancer, and the survival rate of breast cancer patients has increased because of this receptor's inhibition. However, tumors have shown resistance to...
2.
Reissig T, Ladigan-Badura S, Steinberg A, Maghnouj A, Li T, Verdoodt B, et al.
Mol Oncol
. 2023 Aug;
17(11):2396-2414.
PMID: 37604687
Although approximately half of all metastatic colorectal cancers (mCRCs) harbour mutations in KRAS or NRAS, hardly any progress has been made regarding targeted treatment for this group over the last...
3.
Althaus J, Nilius-Eliliwi V, Maghnouj A, Doring S, Schroers R, Hudecek M, et al.
Cancer Immunol Immunother
. 2023 Apr;
72(8):2573-2583.
PMID: 37052701
Chimeric antigen receptors (CARs) have improved cancer immunotherapy in recent years. Immune cells, such as Natural killer cells (NK-cells) or T cells, are used as effector cells in CAR-therapy. NK92-cells,...
4.
Vangala D, Ladigan S, Liffers S, Noseir S, Maghnouj A, Gotze T, et al.
Genome Med
. 2021 Jul;
13(1):116.
PMID: 34271981
Background: The development of secondary resistance (SR) in metastatic colorectal cancer (mCRC) treated with anti-epidermal growth factor receptor (anti-EGFR) antibodies is not fully understood at the molecular level. Here we...
5.
Gehmeyr J, Maghnouj A, Tjaden J, Vorgerd M, Hahn S, Matschke V, et al.
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33671638
The vascular endothelial growth factor (VEGF) is well known for its wide-ranging functions, not only in the vascular system, but also in the central (CNS) and peripheral nervous system (PNS)....
6.
Mika T, Ladigan-Badura S, Maghnouj A, Mustafa B, Klein-Scory S, Baraniskin A, et al.
Front Oncol
. 2020 Dec;
10:568056.
PMID: 33363008
In relapsed and refractory multiple myeloma (MM), adoptive cell therapies (ACT) including CAR-T-cells are under clinical investigation. However, relapse due to T-cell exhaustion or limited persistence is an obstacle. Before...
7.
Mika T, Maghnouj A, Klein-Scory S, Ladigan-Badura S, Baraniskin A, Thomson J, et al.
Front Mol Biosci
. 2020 Jun;
7:84.
PMID: 32500079
CD19-directed CAR-T-cells (CD19-CAR) have demonstrated remarkable clinical results in patients suffering from refractory or relapsed lymphoma and acute lymphoblastic leukemia. In order to further optimize follow-up, to explain treatment failure,...
8.
Stepath M, Zulch B, Maghnouj A, Schork K, Turewicz M, Eisenacher M, et al.
J Proteome Res
. 2019 Dec;
19(2):926-937.
PMID: 31814417
We evaluated the quantification strategies label-free (LF), stable isotope labeling by amino acids in cell culture (SILAC), and tandem mass tags (TMT) and their performance in quantification of proteins and...
9.
Xie K, Varatnitskaya M, Maghnouj A, Bader V, Winklhofer K, Hahn S, et al.
Redox Biol
. 2019 Oct;
28:101344.
PMID: 31639650
Neutrophils produce a cocktail of oxidative species during the so-called oxidative burst to attack phagocytized bacteria. However, little is known about the neutrophils' redox homeostasis during the oxidative burst and...
10.
Weisner J, Landel I, Reintjes C, Uhlenbrock N, Trajkovic-Arsic M, Dienstbier N, et al.
Cancer Res
. 2019 Mar;
79(9):2367-2378.
PMID: 30858154
Aberrations within the PI3K/AKT signaling axis are frequently observed in numerous cancer types, highlighting the relevance of these pathways in cancer physiology and pathology. However, therapeutic interventions employing AKT inhibitors...