Abdelouahid Maghnouj
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Explore the profile of Abdelouahid Maghnouj including associated specialties, affiliations and a list of published articles.
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28
Citations
846
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Recent Articles
11.
Hammoud M, Yosef H, Lechtonen T, Aljakouch K, Schuler M, Alsaidi W, et al.
Sci Rep
. 2018 Oct;
8(1):15278.
PMID: 30323297
Monitoring the drug efficacy or resistance in vitro is usually carried out by measuring the response of single few proteins. However, observation of single proteins instead of an integral cell...
12.
Loosse C, Pawlas M, Bukhari H, Maghnouj A, Hahn S, Marcus K, et al.
Cell Signal
. 2015 Nov;
28(1):100-9.
PMID: 26521045
Nuclear spheres are composed of FE65, TIP60, BLM and other yet unknown proteins. The amyloid precursor protein plays a central role for the generation of these highly toxic aggregates in...
13.
In vitro prediction of the efficacy of molecularly targeted cancer therapy by Raman spectral imaging
Yosef H, Mavarani L, Maghnouj A, Hahn S, El-Mashtoly S, Gerwert K
Anal Bioanal Chem
. 2015 Jul;
407(27):8321-31.
PMID: 26168967
Mutational acquired resistance is a major challenge in cancer therapy. Somatic tumours harbouring some oncogenic mutations are characterised by a high mortality rate. Surprisingly, preclinical evaluation methods do not show...
14.
El-Mashtoly S, Yosef H, Petersen D, Mavarani L, Maghnouj A, Hahn S, et al.
Anal Chem
. 2015 Jun;
87(14):7297-304.
PMID: 26075314
Predictions about the cellular efficacy of drugs tested in vitro are usually based on the measured responses of a few proteins or signal transduction pathways. However, cellular proteins are highly...
15.
El-Mashtoly S, Niedieker D, Petersen D, Krauss S, Freier E, Maghnouj A, et al.
Biophys J
. 2014 May;
106(9):1910-20.
PMID: 24806923
Coherent anti-Stokes Raman scattering (CARS) is an emerging tool for label-free characterization of living cells. Here, unsupervised multivariate analysis of CARS datasets was used to visualize the subcellular compartments. In...
16.
Kumar S, Appukuttan A, Maghnouj A, Hahn S, Reusch H, Ladilov Y
Apoptosis
. 2014 May;
19(7):1069-79.
PMID: 24781801
Apoptosis of vascular smooth muscle cells (VSMC) significantly contributes to the instability of advanced atherosclerotic plaques. Oxygen radicals are an important cause for VSMC death. However, the precise mechanism of...
17.
Zollner H, Hahn S, Maghnouj A
Methods Mol Biol
. 2013 Oct;
1095:177-90.
PMID: 24166313
Deregulation of microRNAs (miRNAs) has been attributed to almost any human disease analyzed to date. This calls for models and experimental strategies for functional analyses of miRNAs enabling miRNA overexpression...
18.
Zollner H, Hahn S, Maghnouj A
Methods Mol Biol
. 2013 Oct;
1095:121-34.
PMID: 24166308
Quantification of microRNAs (miRNAs) in cells or primary tissues is one of the most important steps in elucidating their biological functions. However, miRNAs are challenging molecules for PCR amplification due...
19.
Birkenkamp-Demtroder K, Hahn S, Mansilla F, Thorsen K, Maghnouj A, Christensen R, et al.
PLoS One
. 2013 Sep;
8(9):e73593.
PMID: 24039993
Keratin 23 (KRT23) is strongly expressed in colon adenocarcinomas but absent in normal colon mucosa. Array based methylation profiling of 40 colon samples showed that the promoter of KRT23 was...
20.
Baraniskin A, Nopel-Dunnebacke S, Ahrens M, Jensen S, Zollner H, Maghnouj A, et al.
Int J Cancer
. 2012 Aug;
132(2):E48-57.
PMID: 22907602
Improved non-invasive strategies for early cancer detection are urgently needed to reduce morbidity and mortality. Non-coding RNAs, such as microRNAs and small nucleolar RNAs, have been proposed as biomarkers for...