Aaron C Goldstrohm
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Explore the profile of Aaron C Goldstrohm including associated specialties, affiliations and a list of published articles.
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38
Citations
1578
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Recent Articles
1.
Connacher R, Roden R, Huang K, Korte A, Yeruva S, Dittbenner N, et al.
Nucleic Acids Res
. 2024 Oct;
52(20):12669-12688.
PMID: 39351871
The essential Drosophila RNA-binding protein Brain Tumor (Brat) represses specific genes to control embryogenesis and differentiation of stem cells. In the brain, Brat functions as a tumor suppressor that diminishes...
2.
Haugen R, Barnier C, Elrod N, Luo H, Jensen M, Ji P, et al.
RNA
. 2024 Apr;
30(7):866-890.
PMID: 38627019
The sequence-specific RNA-binding protein Pumilio (Pum) controls development; however, the network of mRNAs that it regulates remains incompletely characterized. In this study, we use knockdown and knockout approaches coupled with...
3.
McKenney K, Connacher R, Dunshee E, Goldstrohm A
RNA
. 2024 Jan;
30(4):448-462.
PMID: 38282416
This report describes a chemiluminescence-based detection method for RNAs on northern blots, designated Chemi-Northern. This approach builds on the simplicity and versatility of northern blotting, while dispensing of the need...
4.
McKenney K, Connacher R, Dunshee E, Goldstrohm A
bioRxiv
. 2023 Oct;
PMID: 37873431
This report describes a chemiluminescence-based detection method for RNAs on northern blots, designated Chemi-Northern. This approach builds on the simplicity and versatility of northern blotting, while dispensing of the need...
5.
Arvola R, Goldstrohm A
Methods Mol Biol
. 2023 Oct;
2723:93-111.
PMID: 37824066
The poly-adenosine, or poly(A) tail, plays key roles in controlling the stability and translation of messenger RNAs in all eukaryotes, and, as such, facile assays that can measure poly(A) length...
6.
Haugen R, Barnier C, Elrod N, Luo H, Jensen M, Ji P, et al.
bioRxiv
. 2023 Sep;
PMID: 37693497
The sequence-specific RNA-binding protein Pumilio controls development of ; however, the network of mRNAs that it regulates remains incompletely characterized. In this study, we utilize knockdown and knockout approaches coupled...
7.
Haugen R, Arvola R, Connacher R, Roden R, Goldstrohm A
J Biol Chem
. 2022 Jul;
298(9):102270.
PMID: 35850301
Pumilio is a sequence-specific RNA-binding protein that controls development, stem cell fate, and neurological functions in Drosophila. Pumilio represses protein expression by destabilizing target mRNAs in a manner dependent on...
8.
Enwerem I, Elrod N, Chang C, Lin A, Ji P, Bohn J, et al.
RNA
. 2021 Jan;
27(4):445-464.
PMID: 33397688
Pumilio paralogs, PUM1 and PUM2, are sequence-specific RNA-binding proteins that are essential for vertebrate development and neurological functions. PUM1&2 negatively regulate gene expression by accelerating degradation of specific mRNAs. Here,...
9.
Abshire E, Hughes K, Diao R, Pearce S, Gopalakrishna S, Trievel R, et al.
J Biol Chem
. 2020 Aug;
295(44):15112-15133.
PMID: 32839274
Nocturnin (NOCT) is a eukaryotic enzyme that belongs to a superfamily of exoribonucleases, endonucleases, and phosphatases. In this study, we analyze the expression, processing, localization, and cellular functions of human...
10.
Wolfe M, Schagat T, Paulsen M, Magnuson B, Ljungman M, Park D, et al.
RNA
. 2020 Aug;
26(11):1680-1703.
PMID: 32753408
The human PUF-family proteins, PUM1 and PUM2, posttranscriptionally regulate gene expression by binding to a PUM recognition element (PRE) in the 3'-UTR of target mRNAs. Hundreds of PUM1/2 targets have...