A Townsend-Nicholson
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Explore the profile of A Townsend-Nicholson including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
387
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Recent Articles
1.
Jayasinghe S, Townsend-Nicholson A
Lab Chip
. 2006 Jul;
6(8):1086-90.
PMID: 16874383
Electrospraying, or electrohydrodynamic jetting, is one of several jet-based technologies being explored to process living biological organisms. One of the key advantages of electrospraying is its ability to deposit advanced...
2.
Liu M, King B, Dunn P, Rong W, Townsend-Nicholson A, Burnstock G
J Pharmacol Exp Ther
. 2001 Feb;
296(3):1043-50.
PMID: 11181939
Using voltage-clamp procedures on Xenopus oocytes, agonist-evoked ionic currents by P2X receptors resulting from the coexpression of P2X(2) and P2X(3) subunits were compared against the agonist responses of homomeric P2X(2)...
3.
Hoebertz A, Townsend-Nicholson A, Glass R, Burnstock G, Arnett T
Bone
. 2000 Oct;
27(4):503-10.
PMID: 11033445
Extracellular nucleotides acting through P2 receptors elicit a wide range of responses in many cell types. There is increasing evidence that adenosine triphosphate (ATP) may function as an important local...
4.
King B, Townsend-Nicholson A
J Auton Nerv Syst
. 2000 Jun;
81(1-3):164-70.
PMID: 10869716
The beginning of the last decade heralded three important and sequential developments in our understanding of cell-to-cell signalling by extracellular ATP via its cell surface receptors, the P2 purinoceptors. One...
5.
Glass R, Townsend-Nicholson A, Burnstock G
Cell Tissue Res
. 2000 Jun;
300(2):295-306.
PMID: 10867824
The expression of the seven P2X receptor subtypes and of two P2Y receptors was examined immunohistochemically and by in situ hybridisation in thymi of adult male rats. P2X4, P2Y2 and...
6.
King B, Townsend-Nicholson A, Wildman S, Thomas T, Spyer K, Burnstock G
J Neurosci
. 2000 Jun;
20(13):4871-7.
PMID: 10864944
Transcripts for P2X(2) and P2X(6) subunits are present in rat CNS and frequently colocalize in the same brainstem nuclei. When rat P2X(2) (rP2X(2)) and rat P2X(6) (rP2X(6)) receptors were expressed...
7.
Meyer M, Clarke J, Patel K, Townsend-Nicholson A, Burnstock G
Dev Dyn
. 1999 Feb;
214(2):152-8.
PMID: 10030594
Responses to extracellular nucleotides (e.g., ATP, ADP, etc.) have been demonstrated in a number of embryonic cell types suggesting they may be important signalling molecules during embryonic development. Here the...
8.
Townsend-Nicholson A, King B, Wildman S, Burnstock G
Brain Res Mol Brain Res
. 1999 Feb;
64(2):246-54.
PMID: 9931497
We have cloned and functionally characterised the mouse orthologue of the P2X4 receptor, mP2X4, and a splice variant of this receptor, mP2X4a. mP2X4 is 388 amino acids in length and...
9.
Camp D, Green J, Kaiser S, Moni R, Townsend-Nicholson A, Schofield P, et al.
Bioorg Med Chem Lett
. 1999 Jan;
8(6):691-4.
PMID: 9871584
Silicon-based microphysiometry, measuring extracellular acidification rate of cells in culture, demonstrated that a series of diimidazo[1,2-c:4',5'-e]pyrimidines were agonists at the human adenosine A1 receptor. 5-amino-7,8-dihydro-3-ribofuranose-8-(R)-(phenyl)-3H-diimidazo [1,2-c:4',5'-e]pyrimidine (2a) had an EC50...
10.
King B, Townsend-Nicholson A, Burnstock G
Trends Pharmacol Sci
. 1999 Jan;
19(12):506-14.
PMID: 9871413
In the past five years, an extended series (P2Y1-n) of metabotropic nucleotide (P2) receptors has been cloned from vertebrate tissues; these receptors are activated by either ATP or UTP, or...