A Shahinian
Overview
Explore the profile of A Shahinian including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
31
Citations
4127
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0
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Recent Articles
1.
Conners L, Betcher A, Shahinian A, Janda P
Case Rep Neurol Med
. 2019 Nov;
2019:9317916.
PMID: 31687237
Stiff-person syndrome (SPS) is an uncommon neurological disorder characterized by significant rigidity and muscle spasms primarily affecting the truncal and proximal musculature. Furthermore, a wide-based gait with functional impairment is...
2.
Alauddin M, Shahinian A, Gordon E, Bading J, Conti P
J Nucl Med
. 2001 Nov;
42(11):1682-90.
PMID: 11696640
Unlabelled: The gene for herpes simplex virus thymidine kinase (HSV-tk) is widely used as a suicide gene in experimental gene therapy of cancer. 9-(4-Fluoro-3-hydroxymethylbutyl)guanine (FHBG) is an antiviral nucleoside analog...
3.
Tafuri A, Shahinian A, Bladt F, Yoshinaga S, Jordana M, Wakeham A, et al.
Nature
. 2001 May;
409(6816):105-9.
PMID: 11343123
The outcome of T-cell responses after T-cell encounter with specific antigens is modulated by co-stimulatory signals, which are required for both lymphocyte activation and development of adaptive immunity. ICOS, an...
4.
Bonnard M, Mirtsos C, Suzuki S, Graham K, Huang J, Ng M, et al.
EMBO J
. 2000 Sep;
19(18):4976-85.
PMID: 10990461
Induction of NF-kappaB-dependent transcription requires phosphorylation and subsequent degradation of I-kappaB, an inhibitor of NF-kappaB, followed by nuclear translocation and DNA binding of NF-kappaB. Tumor necrosis factor receptor-associated factor 2...
5.
Yoshinaga S, Whoriskey J, Khare S, Sarmiento U, Guo J, Horan T, et al.
Nature
. 2000 Jan;
402(6763):827-32.
PMID: 10617205
T-cell activation requires co-stimulation through receptors such as CD28 and antigen-specific signalling through the T-cell antigen receptor. Here we describe a new murine costimulatory receptor-ligand pair. The receptor, which is...
6.
Nguyen L, Duncan G, Mirtsos C, Ng M, Speiser D, Shahinian A, et al.
Immunity
. 1999 Oct;
11(3):379-89.
PMID: 10514016
Tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) can interact with various members of the TNF receptor family. Previously, we reported that TRAF2-deficient mice die prematurely and have elevated serum...
7.
Alauddin M, Shahinian A, Kundu R, Gordon E, Conti P
Nucl Med Biol
. 1999 Jun;
26(4):371-6.
PMID: 10382839
Preparation of 9-[(3-18F-fluoro-1-hydroxy-2-propoxy)methyl]-guanine ([18F]-FHPG) for clinical use, and its evaluation as a positron emission tomography (PET) imaging agent for gene incorporation and expression in tumors are reported. In vitro studies...
8.
Woo M, Hakem R, Soengas M, Duncan G, Shahinian A, Kagi D, et al.
Genes Dev
. 1998 Apr;
12(6):806-19.
PMID: 9512515
Caspases are fundamental components of the mammalian apoptotic machinery, but the precise contribution of individual caspases is controversial. CPP32 (caspase 3) is a prototypical caspase that becomes activated during apoptosis....
9.
Yeh W, de la Pompa J, McCurrach M, Shu H, Elia A, Shahinian A, et al.
Science
. 1998 Apr;
279(5358):1954-8.
PMID: 9506948
FADD (also known as Mort-1) is a signal transducer downstream of cell death receptor CD95 (also called Fas). CD95, tumor necrosis factor receptor type 1 (TNFR-1), and death receptor 3...
10.
Yoshida H, Nishina H, Takimoto H, Marengere L, Wakeham A, Bouchard D, et al.
Immunity
. 1998 Feb;
8(1):115-24.
PMID: 9462517
NF-ATc1 is a member of a family of genes that encodes the cytoplasmic component of the nuclear factor of activated T cells (NF-AT). In activated T cells, nuclear NF-AT binds...