A Robin Temming
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Explore the profile of A Robin Temming including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
145
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Recent Articles
1.
Exel C, Tamminga S, Man-Bovenkerk S, Temming A, Hendriks A, Spaninks M, et al.
Vet Microbiol
. 2025 Jan;
302:110403.
PMID: 39842365
Staphylococcus aureus (S. aureus) is one of the major causes of bovine mastitis, a disease with detrimental effects on health and wellbeing. Current control measures are costly, laborious and not...
2.
Szittner Z, Bentlage A, Temming A, Schmidt D, Visser R, Lissenberg-Thunnissen S, et al.
Front Immunol
. 2023 Oct;
14:1225603.
PMID: 37868955
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) can occur due to maternal IgG antibodies targeting platelet antigens, causing life-threatening bleeding in the neonate. However, the disease manifests itself in only a...
3.
Di Carluccio C, Soriano-Maldonado P, Berni F, de Haas C, Temming A, Hendriks A, et al.
ACS Cent Sci
. 2022 Oct;
8(10):1383-1392.
PMID: 36313161
Wall teichoic acids (WTAs) are glycopolymers decorating the surface of Gram-positive bacteria and potential targets for antibody-mediated treatments against , including methicillin-resistant (MRSA) strains. Through a combination of glycan microarray,...
4.
Temming A, Tammes Buirs M, Bentlage A, Treffers L, Feringa H, de Taeye S, et al.
Front Immunol
. 2021 Apr;
12:594773.
PMID: 33790888
Antibody-mediated blood disorders ensue after auto- or alloimmunization against blood cell antigens, resulting in cytopenia. Although the mechanisms of cell destruction are the same as in immunotherapies targeting tumor cells,...
5.
Heemskerk N, Gruijs M, Temming A, Heineke M, Gout D, Hellingman T, et al.
J Clin Invest
. 2021 Feb;
131(6).
PMID: 33561014
Most clinically used anticancer mAbs are of the IgG isotype, which can eliminate tumor cells through NK cell-mediated antibody-dependent cellular cytotoxicity and macrophage-mediated antibody-dependent phagocytosis. IgG, however, ineffectively recruits neutrophils...
6.
Brinkhaus M, Douwes R, Bentlage A, Temming A, de Taeye S, Tammes Buirs M, et al.
J Immunol
. 2020 Nov;
205(12):3456-3467.
PMID: 33188070
Abs of the IgG isotype mediate effector functions like Ab-dependent cellular cytotoxicity and Ab-dependent cellular phagocytosis by Fc interactions with FcγRs and complement-dependent cytotoxicity upon IgG-Fc binding to C1q. In...
7.
Temming A, Bentlage A, de Taeye S, Bosman G, Lissenberg-Thunnissen S, Derksen N, et al.
Mol Immunol
. 2020 Sep;
127:79-86.
PMID: 32947169
Immunoglobulin G (IgG) antibodies are important for protection against pathogens and exert effector functions through binding to IgG-Fc receptors (FcγRs) on myeloid and natural killer cells, resulting in destruction of...
8.
Temming A, Dekkers G, van de Bovenkamp F, Plomp H, Bentlage A, Szittner Z, et al.
Sci Rep
. 2020 Jul;
10(1):12560.
PMID: 32703963
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
9.
Temming A, de Taeye S, de Graaf E, de Neef L, Dekkers G, Bruggeman C, et al.
J Immunol
. 2019 Nov;
203(12):3126-3135.
PMID: 31748349
Ab-dependent cellular cytotoxicity (ADCC) is one of the most important effector mechanisms of tumor-targeting Abs in current immunotherapies. In ADCC and other Ab-dependent activation of myeloid effector cells, close cell-cell...
10.
Temming A, Dekkers G, van de Bovenkamp F, Plomp H, Bentlage A, Szittner Z, et al.
Sci Rep
. 2019 Jul;
9(1):9995.
PMID: 31292524
The precise mechanisms underlying anti-inflammatory effects of intravenous immunoglobulin (IVIg) therapies remain elusive. The sialylated IgG fraction within IVIg has been shown to be therapeutically more active in mouse models....