» Authors » A Raquel Esteves

A Raquel Esteves

Explore the profile of A Raquel Esteves including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 27
Citations 649
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Munoz-Pinto M, Candeias E, Melo-Marques I, Esteves A, Maranha A, Magalhaes J, et al.
Mol Neurodegener . 2024 Oct; 19(1):78. PMID: 39449004
Background: In Parkinson's patients, intestinal dysbiosis can occur years before clinical diagnosis, implicating the gut and its microbiota in the disease. Recent evidence suggests the gut microbiota may trigger body-first...
2.
Pereira-Santos A, Candeias E, Magalhaes J, Empadinhas N, Esteves A, Cardoso S
Biochim Biophys Acta Mol Basis Dis . 2024 Apr; 1870(5):167167. PMID: 38626829
The microbial toxin β-N-methylamino-L-alanine (BMAA), which is derived from cyanobacteria, targets neuronal mitochondria, leading to the activation of neuronal innate immunity and, consequently, neurodegeneration. Although known to modulate brain inflammation,...
3.
Magalhaes J, Candeias E, Melo-Marques I, Silva D, Esteves A, Empadinhas N, et al.
Cell Mol Life Sci . 2023 May; 80(6):166. PMID: 37249642
Parkinson's disease (PD) is a multifactorial neurodegenerative disease characterized by the loss of dopaminergic neurons in the midbrain. In the prodromal phase several autonomic symptoms including orthostatic hypotension and constipation...
4.
Esteves A, Silva D, Banha D, Candeias E, Guedes B, Cardoso S
Redox Biol . 2023 Apr; 63:102714. PMID: 37120929
Sporadic Parkinson's disease (sPD) is a complex multifactorial disorder which etiology remains elusive. Several mechanisms have been described to contribute to PD development namely mitochondrial dysfunction, activation of inflammatory pathways...
5.
Esteves A, Munoz-Pinto M, Nunes-Costa D, Candeias E, Silva D, Magalhaes J, et al.
Gut . 2021 Nov; 72(1):73-89. PMID: 34836918
Objective: Idiopathic Parkinson's disease (PD) is characterised by alpha-synuclein (aSyn) aggregation and death of dopaminergic neurons in the midbrain. Recent evidence posits that PD may initiate in the gut by...
6.
Silva D, Candeias E, Esteves A, Magalhaes J, Ferreira I, Nunes-Costa D, et al.
J Neuroinflammation . 2020 Nov; 17(1):332. PMID: 33153477
Background: After decades of research recognizing it as a complex multifactorial disorder, sporadic Alzheimer's disease (sAD) still has no known etiology. Adding to the myriad of different pathways involved, bacterial...
7.
Esteves A, Filipe F, Magalhaes J, Silva D, Cardoso S
Mol Neurobiol . 2019 Jan; 56(8):5654-5670. PMID: 30661206
Macroautophagy impairment plays a key role in sporadic Alzheimer's disease (sAD) neurodegenerative process. Nevertheless, the mechanism(s) that lead to a deficiency in macroautophagy in AD remains elusive. In this work,...
8.
Hiremathad A, Keri R, Esteves A, Cardoso S, Chaves S, Santos M
Eur J Med Chem . 2018 Feb; 148:255-267. PMID: 29466775
Alzheimer's disease (AD) is a severe age-dependent neurodegenerative disorder affecting millions of people, with no cure so far. The current treatments only achieve some temporary amelioration of the cognition symptoms....
9.
Hiremathad A, Chand K, Tolayan L, Rajeshwari , Keri R, Esteves A, et al.
J Inorg Biochem . 2017 Nov; 179:82-96. PMID: 29182921
A series of (3-hydroxy-4-pyridinone)-benzofuran hybrids have been developed and studied as potential multitargeting drugs for Alzheimer's disease (AD). Their design envisaged mainly to mimic the donepezil drug, a marketed inhibitor...
10.
Esteves A, Cardoso S
Neuroscientist . 2016 Jan; 23(1):16-26. PMID: 26740081
Mutations in leucine-rich repeat kinase 2 ( lrrk2) gene cause inherited Parkinson's disease (PD), and common variants in lrrk2 are a risk factor for sporadic PD. The neuropathology associated with...