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A Monks

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Articles 58
Citations 5340
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Recent Articles
1.
Zoppoli G, Solier S, Reinhold W, Liu H, Connelly Jr J, Monks A, et al.
Oncogene . 2011 Jul; 31(4):403-18. PMID: 21765476
CHEK2 encodes a serine/threonine kinase (Chk2) activated by ATM in response to DNA double-strand breaks. On the one hand, CHEK2 has been described as a tumor suppressor with proapoptotic, cell-cycle...
2.
Peters A, Smythe A, Wu L, Monks A, Boyd M, Shoemaker R
Oncol Rep . 2011 May; 1(5):907-11. PMID: 21607464
The relationship between cellular levels of mRNA coding for DNA topoisomerase II, both the alpha and beta isoforms, and in vitro sensitivity to anticancer drugs were evaluated. Using a sensitive...
3.
Rybak S, Lin J, Newton D, Kung H, Monks A, Chen H, et al.
Int J Oncol . 2011 May; 5(5):1171-6. PMID: 21559696
MAP 30 and GAP 31 are plant proteins isolated from Momordica charantia and Gelonium multiflorum, respectively. They have recently been shown to inhibit HIV-1 infection and replication. These proteins also...
4.
Scheffer G, de Jong M, Monks A, Flens M, Hose C, Izquierdo M, et al.
Br J Cancer . 2002 Jun; 86(12):1943-50. PMID: 12085191
The rat monoclonal antibody LMR-12 was shown earlier to react with a plasma membrane protein, upregulated in multidrug-resistant cell lines. In this study, we observed distinct LMR-12 staining in 36...
5.
Silva G, Cui B, Chavez D, You M, Chai H, Rasoanaivo P, et al.
J Nat Prod . 2002 Jan; 64(12):1514-20. PMID: 11754602
Nine tropane alkaloid aromatic esters (1-9) were isolated from the roots of Erythroxylum pervillei by following their potential to reverse multidrug-resistance with vinblastine-resistant oral epidermoid carcinoma (KB-V1) cells. All isolates,...
6.
Grem J, Danenberg K, Behan K, Parr A, Young L, Danenberg P, et al.
Clin Cancer Res . 2001 Apr; 7(4):999-1009. PMID: 11309351
Purpose: To determine the expression of three targets of 5-fluorouracil (5-FU) and 5-fluoro-2'-deoxyuridine (FdUrd) in human tumor cell lines and to compare these with the 50% growth inhibition concentrations (GI(50))...
7.
Meinhold-Heerlein I, Stenner-Liewen F, Liewen H, Kitada S, Krajewska M, Krajewski S, et al.
Am J Pathol . 2001 Apr; 158(4):1335-44. PMID: 11290551
Fas-associated phosphatase-1 (FAP-1) is a protein-tyrosine phosphatase that binds the cytosolic tail of Fas (Apo1, CD95), presumably regulating Fas-induced apoptosis. Elevations of FAP-1 protein levels in some tumor cell lines...
8.
Yu L, Matias J, Scudiero D, Hite K, Monks A, Sausville E, et al.
Drug Metab Dispos . 2001 Feb; 29(3):304-12. PMID: 11181500
Cytochrome P450 (P450) enzyme expression patterns were determined for a panel of 60 human tumor cell lines, representing nine tumor tissue types, used by the National Cancer Institute (NCI) Anticancer...
9.
Taverna P, Liu L, Hanson A, Monks A, Gerson S
Cancer Chemother Pharmacol . 2001 Jan; 46(6):507-16. PMID: 11138465
Purpose And Methods: The lack of a functional DNA mismatch repair (MMR) pathway has been recognized as a common characteristic of several different types of human cancers due to mutation...
10.
Zapata J, Krajewska M, Krajewski S, Kitada S, Welsh K, Monks A, et al.
J Immunol . 2000 Oct; 165(9):5084-96. PMID: 11046039
TNFR-associated factors (TRAFs) constitute a family of adapter proteins that associate with particular TNF family receptors. Humans and mice contain six TRAF genes, but little is known about their in...