A L Gurney
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Explore the profile of A L Gurney including associated specialties, affiliations and a list of published articles.
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32
Citations
2458
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Recent Articles
21.
Gurney A, Wong S, Henzel W, de Sauvage F
Proc Natl Acad Sci U S A
. 1995 Jun;
92(12):5292-6.
PMID: 7777500
c-Mpl, a member of the hematopoietic cytokine receptor family, is the receptor for thrombopoietin. To investigate signal transduction by c-Mpl, a chimeric receptor, composed of the extracellular domain of human...
22.
Gurney A, Kuang W, Xie M, Malloy B, Eaton D, de Sauvage F
Blood
. 1995 Feb;
85(4):981-8.
PMID: 7849319
Thrombopoietin (TPO), the ligand for c-mpl, is a novel cytokine comprising an amino terminal domain with homology to erythropoietin and a glycosylated carboxyl terminal domain that does not bear overall...
23.
Gurney A, de Sauvage F, Moore M
Science
. 1994 Sep;
265(5177):1445-7.
PMID: 8073287
Thrombopoietin (TPO) is a cytokine that is involved in the regulation of platelet production. The receptor for TPO is c-Mpl. To further investigate the role and specificity of this receptor...
24.
Gurney A, Park E, Liu J, Giralt M, McGrane M, Patel Y, et al.
J Nutr
. 1994 Aug;
124(8 Suppl):1533S-1539S.
PMID: 8064415
The impact of nutrients on gene expression has become an area of considerable interest as the number of genes coding for key regulatory proteins in metabolic pathways are studied in...
25.
de Sauvage F, Hass P, Spencer S, Malloy B, Gurney A, Spencer S, et al.
Nature
. 1994 Jun;
369(6481):533-8.
PMID: 8202154
Physiological platelet synthesis is thought to require the humoral activities of meg-CSF and thrombopoietin, which respectively promote proliferation and maturation of megakaryocytic cells. A meg-CSF/thrombopoietin-like protein that is present in...
26.
Campbell C, Huang A, Gurney A, Kessler P, Hewitt J, Williams B
Oncogene
. 1994 Feb;
9(2):583-95.
PMID: 8290269
Transcription of the WT1 locus is restricted, both temporally and spatially, to a subset of epithelial cells in mammalian kidneys and gonads. WT1, one of the two divergent transcripts mapping...
27.
Park E, Gurney A, Nizielski S, Hakimi P, Cao Z, Moorman A, et al.
J Biol Chem
. 1993 Jan;
268(1):613-9.
PMID: 8093246
The gene for phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK) is expressed in a tissue-specific manner in the liver, kidney, and adipose tissue and is regulated by hormones including cAMP and...
28.
Gurney A, Park E, Giralt M, Liu J, Hanson R
J Biol Chem
. 1992 Sep;
267(25):18133-9.
PMID: 1325459
Jun homodimers and Fos/Jun heterodimers bind to the gene for phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK) at three sites within the first 350 base pairs of the promoter. These include...
29.
Giralt M, Park E, Gurney A, Liu J, Hakimi P, Hanson R
J Biol Chem
. 1991 Nov;
266(32):21991-6.
PMID: 1657985
Transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK) in the liver is regulated by many hormones including thyroid hormone (T3). In order to...
30.
Liu J, Park E, Gurney A, Roesler W, Hanson R
J Biol Chem
. 1991 Oct;
266(28):19095-102.
PMID: 1655770
The cis elements involved in the cAMP regulation of transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK) were studied by introducing a series of block mutations (10-15...