A L Gurney
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Explore the profile of A L Gurney including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
2458
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Recent Articles
11.
Li H, Chen J, Huang A, Stinson J, Heldens S, Foster J, et al.
Proc Natl Acad Sci U S A
. 2000 Jan;
97(2):773-8.
PMID: 10639155
IL-17 is a T cell-derived cytokine that may play an important role in the initiation or maintenance of the proinflammatory response. Whereas expression of IL-17 is restricted to activated T...
12.
Xie M, Holcomb I, Deuel B, Dowd P, Huang A, Vagts A, et al.
Cytokine
. 1999 Oct;
11(10):729-35.
PMID: 10525310
We have identified a novel fibroblast growth factor, FGF-19, the most distant member of the FGF family described to date. FGF-19 is a high affinity, heparin dependent ligand for FGFR4...
13.
Yang R, Mark M, Gurney A, Godowski P
J Immunol
. 1999 Jul;
163(2):639-43.
PMID: 10395652
Human Toll-like receptor 2 (TLR2) is a signaling receptor that responds to LPS and activates NF-kappaB. Here, we investigate further the events triggered by TLR2 in response to LPS. We...
14.
Gurney A, Marsters S, Huang R, Pitti R, Mark D, Baldwin D, et al.
Curr Biol
. 1999 Mar;
9(4):215-8.
PMID: 10074428
The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate diverse biological functions, including cell proliferation, differentiation, and survival [1] [2] [3]. We have identified a new TNF-related...
15.
Pitti R, Marsters S, Lawrence D, Roy M, Kischkel F, Dowd P, et al.
Nature
. 1999 Jan;
396(6712):699-703.
PMID: 9872321
Fas ligand (FasL) is produced by activated T cells and natural killer cells and it induces apoptosis (programmed cell death) in target cells through the death receptor Fas/Apol/CD95. One important...
16.
Pennica D, Swanson T, Welsh J, Roy M, Lawrence D, Lee J, et al.
Proc Natl Acad Sci U S A
. 1998 Dec;
95(25):14717-22.
PMID: 9843955
Wnt family members are critical to many developmental processes, and components of the Wnt signaling pathway have been linked to tumorigenesis in familial and sporadic colon carcinomas. Here we report...
17.
Yang R, Mark M, Gray A, Huang A, Xie M, Zhang M, et al.
Nature
. 1998 Sep;
395(6699):284-8.
PMID: 9751057
Vertebrates and invertebrates initiate a series of defence mechanisms following infection by Gram-negative bacteria by sensing the presence of lipopolysaccharide (LPS), a major component of the cell wall of the...
18.
Savon S, Hakimi P, Crawford D, Klemm D, Gurney A, Hanson R
J Nutr
. 1997 Feb;
127(2):276-85.
PMID: 9039828
Hepatic expression of the gene for phosphoenolpyruvate carboxykinase (GTP) (PEPCK-C) (EC 4.1.1.32) in birds occurs prior to birth and decreases to negligible levels before hatching, whereas in mammals the gene...
19.
Fielder P, Gurney A, Stefanich E, Marian M, Moore M, de Sauvage F
Blood
. 1996 Mar;
87(6):2154-61.
PMID: 8630374
The involvement of platelets and the c-mpl receptor in the regulation of thrombopoietin (TPO) plasma concentrations and tissue mRNA levels was investigated in both normal mice and mice defective in...
20.
Gurney A, de Sauvage F
Stem Cells
. 1996 Jan;
14 Suppl 1:116-23.
PMID: 11012211
The physiological roles and mechanisms of action of thrombopoietin (TPO) and its receptor c-Mpl have been studied through the analysis of mice genetically deficient in these molecules, as well as...