F J de Sauvage
Overview
Explore the profile of F J de Sauvage including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
2728
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Recent Articles
1.
Andres R, Forgie A, Wyatt S, Chen Q, de Sauvage F, Davies A
Development
. 2001 Oct;
128(19):3685-95.
PMID: 11585795
To define the role of artemin in sympathetic neurone development, we have studied the effect of artemin on the generation, survival and growth of sympathetic neurones in low-density dissociated cultures...
2.
Shou J, Ross S, Koeppen H, de Sauvage F, Gao W
Cancer Res
. 2001 Oct;
61(19):7291-7.
PMID: 11585768
Notch signaling has been widely demonstrated to be responsible for cell fate determination during normal development and implicated in human T-cell leukemia and mouse mammary carcinomas. Here we show that...
3.
Bonifas J, Pennypacker S, Chuang P, McMahon A, Williams M, Rosenthal A, et al.
J Invest Dermatol
. 2001 May;
116(5):739-42.
PMID: 11348463
Mutations in hedgehog signaling pathway genes, especially PTC1 and SMO, are pivotal to the development of basal cell carcinomas. The study of basal cell carcinoma gene expression not only may...
4.
Filippi M, Porteu F, Le Pesteur F, Rameau P, Nogueira M, Debili N, et al.
Exp Hematol
. 2001 Jan;
28(12):1363-72.
PMID: 11146158
To examine whether the in vitro model of embryonic stem (ES) cell hematopoietic differentiation is suitable to study the function of intracytoplasmic regions of cytokine receptors, we used the thrombopoietin...
5.
Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus
Zhang J, Rosenthal A, de Sauvage F, Shivdasani R
Dev Biol
. 2001 Jan;
229(1):188-202.
PMID: 11133163
Hedgehog ligands interact with receptor complexes containing Patched (PTC) and Smoothened (SMO) proteins to regulate many aspects of development. The mutation W535L (SmoM2) in human Smo is associated with basal...
6.
Chen Q, Ghilardi N, Wang H, Baker T, Xie M, Gurney A, et al.
Nature
. 2000 Nov;
407(6806):916-20.
PMID: 11057672
On antigen challenge, T-helper cells differentiate into two functionally distinct subsets, Th1 and Th2, characterized by the different effector cytokines that they secrete. Th1 cells produce interleukin (IL)-2, interferon-gamma (IFN-gamma)...
7.
Chen Q, Solar G, Eaton D, de Sauvage F
Stem Cells
. 2000 Sep;
16 Suppl 2:31-6.
PMID: 11012175
Thrombopoietin is a lineage-dominant cytokine involved primarily in the control of platelet production. The physiological importance of thrombopoietin (TPO) in the regulation of megakaryocyte and platelet production was demonstrated by...
8.
Hongo J, Tsai S, Moffat B, Schroeder K, Jung C, Chuntharapai A, et al.
Hybridoma
. 2000 Sep;
19(4):303-15.
PMID: 11001403
Neurturin (NTN) a structural and functional relative of glial cell line-derived neurotrophic factor, was originally identified based on its ability to support the survival of sympathetic neurons in culture. Similar...
9.
DeCamp D, Thompson T, de Sauvage F, Lerner M
J Biol Chem
. 2000 Jun;
275(34):26322-7.
PMID: 10835429
The 7-pass transmembrane protein Smoothened was investigated for its ability to act as a G-protein-coupled receptor in Xenopus laevis melanophores. A plasmid containing the human Smoothened cDNA insert was transfected...
10.
Murone M, Luoh S, Stone D, Li W, Gurney A, Armanini M, et al.
Nat Cell Biol
. 2000 May;
2(5):310-2.
PMID: 10806483
No abstract available.