A L Bothwell
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Explore the profile of A L Bothwell including associated specialties, affiliations and a list of published articles.
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72
Citations
1924
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Recent Articles
11.
Bothwell A
Immunol Res
. 1999 Sep;
19(2-3):233-43.
PMID: 10493177
Successful xenotransplantation necessitates solving problems of hyperacute rejection and understanding the cellular immune responses that occur. Considerable progress has been made in our understanding of the molecular genetic basis of...
12.
Lawrence M, Foellmer H, Elsworth J, Kim J, Leranth C, Kozlowski D, et al.
Gene Ther
. 1999 Sep;
6(8):1368-79.
PMID: 10467361
An E1, E3 deleted adenovirus vector, serotype 5, carrying the marker gene LacZ was bilaterally microinfused into the caudate nuclei of 10 St Kitts green monkeys. The location and number...
13.
Khodadoust M, Khan K, Bothwell A
J Immunol
. 1999 Jul;
163(2):811-9.
PMID: 10395674
The complexity of IFN-mediated regulation of the murine Ly-6E gene in T cell lines is highlighted by the following observations: 1) multiple regulatory regions are present within different parts of...
14.
Coady M, Mandapati D, Arunachalam B, Jensen K, Maher S, Bothwell A, et al.
Transplantation
. 1999 Jun;
67(11):1461-7.
PMID: 10385086
Background: Polymorphic class I and II major histo-: compatibility complex (MHC) genes are not transcribed in trophoblasts although many immune system cells express these genes constitutively. To study the molecular...
15.
Welte T, Leitenberg D, Dittel B, al-Ramadi B, Xie B, Chin Y, et al.
Science
. 1999 Jan;
283(5399):222-5.
PMID: 9880255
The role of STAT (signal transducer and activator of transcription) proteins in T cell receptor (TCR) signaling was analyzed. STAT5 became immediately and transiently phosphorylated on tyrosine 694 in response...
16.
Maher S, Pflugh D, Larsen N, Rothschild M, Bothwell A
Transplantation
. 1998 Nov;
66(8):1094-100.
PMID: 9808497
Background: Complement regulatory proteins have become important targets to potentially modulate inflammatory reactions or transplant rejection. Since pig into human xenotransplantation could potentially overcome the enormous shortage of donor organs...
17.
al-Ramadi B, Zhang H, Bothwell A
Proc Natl Acad Sci U S A
. 1998 Oct;
95(21):12498-503.
PMID: 9770514
By using antisense RNA, Lck-deficient transfectants of a T helper 2 (Th2) clone have been derived and shown to have a qualitative defect in the T cell receptor signaling pathway....
18.
Khodadoust M, Khan K, Park E, Bothwell A
Blood
. 1998 Sep;
92(7):2399-409.
PMID: 9746780
The murine Ly6-E gene is transcriptionally induced by interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma in a variety of distinct cell types. The mechanism of IFN inducibility in B-cell lines was investigated by...
19.
OHerrin S, Lebowitz M, Bieler J, al-Ramadi B, Utz U, Bothwell A, et al.
J Exp Med
. 1997 Oct;
186(8):1333-45.
PMID: 9334373
Understanding the regulation of cell surface expression of specific peptide-major histocompatibility complex (MHC) complexes is hindered by the lack of direct quantitative analyses of specific peptide-MHC complexes. We have developed...
20.
Sultan P, Murray A, McNiff J, Lorber M, Askenase P, Bothwell A, et al.
Proc Natl Acad Sci U S A
. 1997 Aug;
94(16):8767-72.
PMID: 9238052
Split-thickness pig skin was transplanted on severe combined immunodeficient mice so that pig dermal microvessels spontaneously inosculated with mouse microvessels and functioned to perfuse the grafts. Pig endothelial cells in...