A L Bothwell
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Explore the profile of A L Bothwell including associated specialties, affiliations and a list of published articles.
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Articles
72
Citations
1924
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Recent Articles
1.
al-Ramadi B, Welte T, Fernandez-Cabezudo M, Galadari S, Dittel B, Fu X, et al.
J Immunol
. 2001 Dec;
167(12):6827-33.
PMID: 11739499
Src-protein tyrosine kinases are intimately involved in TCR-initiated signaling in T lymphocytes. One member of this family, Lck, is also involved in CD28-mediated costimulation in Th1 cells. In Th2 lymphocytes,...
2.
Nakayama Y, Weissman S, Bothwell A
Biochem Biophys Res Commun
. 2001 Jul;
285(3):830-7.
PMID: 11453668
Characterization of genes activated by anti-IgM crosslinking of BL2 cells identified one gene, designated BXMAS1, that is predicted to be a novel cell surface receptor. The time course of activation...
3.
Tereb D, Kirkiles-Smith N, Kim R, Wang Y, Rudic R, Schechner J, et al.
Transplantation
. 2001 Jul;
71(11):1622-30.
PMID: 11435975
Background: We have previously demonstrated that human artery grafts transplanted to immunodeficient mice are infiltrated and injured by unsensitized allogeneic human T cells. We extended our investigations to human anti-porcine...
4.
Douglas N, Jacobs H, Bothwell A, Hayday A
Nat Immunol
. 2001 Mar;
2(4):307-15.
PMID: 11276201
c-Myc is associated with cell growth and cycling in many tissues and its deregulated expression is causally implicated in cancer, particularly lymphomagenesis. However, the contribution of c-Myc to lymphocyte development...
5.
Welte T, Leitenberg D, Dittel B, al-Ramadi B, Hansen W, Xie B, et al.
Cold Spring Harb Symp Quant Biol
. 2001 Mar;
64:291-302.
PMID: 11232299
No abstract available.
6.
Nakayama Y, Iwamoto Y, Maher S, Tanaka Y, Bothwell A
Biochem Biophys Res Commun
. 2000 Oct;
277(1):124-7.
PMID: 11027651
Burkitt's lymphoma cell line, BL2 was stimulated by surface BCR cross-linking and altered gene expression was analyzed by RDA methodology. Consistent with previous reports, we detected up-regulated MDC, IL6R and...
7.
Schechner J, Nath A, Zheng L, Kluger M, Hughes C, Lorber M, et al.
Proc Natl Acad Sci U S A
. 2000 Jul;
97(16):9191-6.
PMID: 10890921
We have identified conditions for forming cultured human umbilical vein endothelial cells (HUVEC) into tubes within a three-dimensional gel that on implantation into immunoincompetent mice undergo remodeling into complex microvessels...
8.
Pflugh D, Maher S, Bothwell A
J Immunol
. 2000 Jun;
165(1):313-21.
PMID: 10861067
A new member of the mouse Ly-6SF, designated Ly-6I, has been isolated as a gene homologous to a segment of the Ly-6C gene. A single allelic difference in the mature...
9.
Kim Y, Sonn C, Paik S, Bothwell A
Gene Ther
. 2000 Jun;
7(10):837-43.
PMID: 10845721
Local cytokine concentrations are required for inhibition of tumor growth with less toxic side-effects. However, genetically engineered tumor cells secreting cytokines still induce toxicity and activate bystander cells. To circumvent...
10.
Zheng L, Dengler T, Kluger M, Madge L, Schechner J, Maher S, et al.
J Immunol
. 2000 Apr;
164(9):4665-71.
PMID: 10779771
Graft endothelial cells are primary targets of host CTL-mediated injury in acute allograft rejection. As an in vitro trial of gene therapy to reduce CTL-mediated endothelial injury, we stably transduced...