A E Broadus
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Explore the profile of A E Broadus including associated specialties, affiliations and a list of published articles.
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115
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2116
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Recent Articles
11.
Wysolmerski J, Vasavada R, Foley J, Weir E, Burtis W, Kukreja S, et al.
Cancer Res
. 1996 Mar;
56(5):1043-9.
PMID: 8640759
Humoral hypercalcemia of malignancy (HHM) is caused by the secretion of parathyroid hormone-related protein (PTHrP) by tumor cells, and tumors of squamous histology are the ones most commonly complicated by...
12.
Philbrick W, Wysolmerski J, Galbraith S, Holt E, Orloff J, Yang K, et al.
Physiol Rev
. 1996 Jan;
76(1):127-73.
PMID: 8592727
Parathyroid hormone-related protein (PTHrP) was discovered as a result of a search for the circulating factor secreted by cancers which causes the common paraneoplastic syndrome humoral hypercalcemia of malignancy. Since...
13.
Wysolmerski J, Daifotis A, Broadus A, Philbrick W
Development
. 1995 Nov;
121(11):3539-47.
PMID: 8582268
Parathyroid hormone-related protein (PTHrP) was originally discovered as the tumor product that causes humoral hypercalcemia of malignancy. PTHrP is now known to be widely expressed in many normal fetal tissues...
14.
Plawner L, Philbrick W, Burtis W, Broadus A, Stewart A
J Biol Chem
. 1995 Jun;
270(23):14078-84.
PMID: 7775469
Parathyroid hormone-related protein (PTHrP) is endoproteolytically processed to yield a family of mature secretory forms. These include an amino-terminal, a mid-region, and a carboxyl-terminal form. Prior studies suggested that the...
15.
Burtis W, Gay L, Insogna K, Ellison A, Broadus A
Am J Clin Nutr
. 1994 Sep;
60(3):424-9.
PMID: 8074077
The relative importance of dietary factors in causing hypercalciuria was assessed in 282 unselected patients with calcium oxalate kidney stones. The 124 patients found to be hypercalciuric on either their...
16.
Yang K, dePapp A, Soifer N, Dreyer B, Wu T, Porter S, et al.
Biochemistry
. 1994 Jun;
33(23):7460-9.
PMID: 8003511
Parathyroid hormone-related protein (PTHrP) is expressed by malignant tumors and leads to the syndrome of humoral hypercalcemia of malignancy. It is also expressed by a wide variety of nonmalignant tissues,...
17.
Holt E, Lu C, Dreyer B, Dannies P, Broadus A
J Neurochem
. 1994 Apr;
62(4):1239-46.
PMID: 8133258
The parathyroid hormone-related peptide (PTHrP) gene has been reported to be subject to a wide variety of physiological and pharmacological controls. Two distinct patterns of PTHrP mRNA response have been...
18.
Wysolmerski J, Broadus A, Zhou J, Fuchs E, Milstone L, Philbrick W
Proc Natl Acad Sci U S A
. 1994 Feb;
91(3):1133-7.
PMID: 7508121
Parathyroid hormone-related peptide (PTHrP) was initially discovered as the cause of the syndrome of humoral hypercalcemia of malignancy. Subsequently, the PTHrP gene has been shown to be expressed in a...
19.
Wysolmerski J, Broadus A
Annu Rev Med
. 1994 Jan;
45:189-200.
PMID: 8198376
Hypercalcemia is the most common metabolic complication of cancer. Malignancy-associated hypercalcemia (MAHC) can be divided into two syndromes, humoral hypercalcemia of malignancy (HHM) and local osteolytic hypercalcemia (LOH), based on...
20.
Holt E, Vasavada R, Bander N, Broadus A, Philbrick W
J Biol Chem
. 1993 Sep;
268(27):20639-45.
PMID: 7690760
Tumor production of a parathyroid hormone-related peptide (PTHrP) is a common cause of the syndrome of humoral hypercalcemia of malignancy, which is frequently associated with renal cell carcinomas. Why certain...