A E Broadus
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Explore the profile of A E Broadus including associated specialties, affiliations and a list of published articles.
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Articles
115
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2116
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Recent Articles
1.
Parathyroid hormone-related protein induces spontaneous osteoclast formation via a paracrine cascade
Nakchbandi I, Weir E, Insogna K, Philbrick W, Broadus A
Proc Natl Acad Sci U S A
. 2000 Jun;
97(13):7296-300.
PMID: 10829073
Experiments in vivo have established that tooth eruption fails in the absence of parathyroid hormone (PTH)-related protein (PTHrP) action in the microenvironment of the tooth because of the failure of...
2.
Brines M, Ling Z, Broadus A
Neurosci Lett
. 1999 Oct;
274(1):13-6.
PMID: 10530508
The parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor genes are widely expressed in the CNS and both are highly expressed in the cerebellar granule cell. We have shown previously that...
3.
Brines M, Broadus A
Endocrinology
. 1999 Feb;
140(2):646-51.
PMID: 9927289
PTH-related protein (PTHrP) is a normal product of many excitable cells of the nervous and endocrine systems. Functions of PTHrP in these tissues are, however, currently unknown. Prior study has...
4.
Foley J, Longely B, Wysolmerski J, Dreyer B, Broadus A, Philbrick W
J Invest Dermatol
. 1998 Dec;
111(6):1122-8.
PMID: 9856827
Emerging evidence suggests that parathyroid hormone-related peptide (PTHrP) serves as a regulator of the development and/or differentiation of a number of organs, including endochondral bone, the tooth, and the mammary...
5.
Wysolmerski J, Philbrick W, Dunbar M, Lanske B, Kronenberg H, Broadus A
Development
. 1998 May;
125(7):1285-94.
PMID: 9477327
Parathyroid hormone-related protein (PTHrP) was originally discovered as a tumor product that causes humoral hypercalcemia of malignancy. PTHrP is now known to be widely expressed in normal tissues and growing...
6.
Amling M, Neff L, Tanaka S, Inoue D, Kuida K, Weir E, et al.
J Cell Biol
. 1997 Jan;
136(1):205-13.
PMID: 9008714
Parathyroid hormone-related peptide (PTHrP) appears to play a major role in skeletal development. Targeted disruption of the PTHrP gene in mice causes skeletal dysplasia with accelerated chondrocyte maturation (Amizuka, N.,...
7.
Dunbar M, Wysolmerski J, Broadus A
Am J Med Sci
. 1996 Dec;
312(6):287-94.
PMID: 8969618
Parathyroid hormone-related protein (PTHrP) was originally discovered because of its role in humoral hypercalcemia of malignancy (HHM), a common metabolic complication of many types of cancer. In HHM, PTHrP is...
8.
Holt E, Broadus A, Brines M
J Biol Chem
. 1996 Nov;
271(45):28105-11.
PMID: 8910424
Parathyroid hormone (PTH)-related peptide (PTHrP) is expressed in the adult mammalian brain, but its function is unknown. Here we show that PTHrP and the PTH/PTHrP receptor are products of cerebellar...
9.
Weir E, Philbrick W, Amling M, Neff L, Baron R, Broadus A
Proc Natl Acad Sci U S A
. 1996 Sep;
93(19):10240-5.
PMID: 8816783
Parathyroid hormone-related peptide (PTHrP) was initially identified as a product of malignant tumors that mediates paraneoplastic hypercalcemia. It is now known that the parathyroid hormone (PTH) and PTHrP genes are...
10.
Foley J, Wysolmerski J, Broadus A, Philbrick W
Cancer Res
. 1996 Sep;
56(17):4056-62.
PMID: 8752179
Parathyroid hormone-related protein (PTHrP) is a normal secretory product of a variety of squamous epithelia, including epidermal keratinocytes. Only a subset of squamous carcinomas, however, express the gene at levels...