Interleukin 2 Production by Both Ly2+ and Ly2- T-cell Subsets

Overview

Journal Scand J Immunol

Specialty Allergy & Immunology

Date 1981 Jan 1

PMID 6165078

Citations 13

Authors

L Andrus

S J Prowse

K J Lafferty

Affiliations

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Abstract

Homogeneous T-cell populations produced by activating lymphocytes to I-, K-, or K+ D- region-encoded determinants of the mouse H-2 complex release interleukin 2 when restimulated by concanavalin A. Contrary to earlier reports on the cellular origin of the lymphokine, we find that interleukin 2 production can be either Ly2+ or Ly2- T-cell-dependent.

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