K J Lafferty
Overview
Explore the profile of K J Lafferty including associated specialties, affiliations and a list of published articles.
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Articles
161
Citations
1327
Followers
0
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Recent Articles
1.
Dilts S, Solvason N, Lafferty K
J Autoimmun
. 1999 Nov;
13(3):285-90.
PMID: 10550215
No abstract available.
2.
Dilts S, Lafferty K
J Autoimmun
. 1999 May;
12(4):229-32.
PMID: 10330293
Our studies in the NOD mouse demonstrate that the autoimmune response can be either benign or malignant. In the former case </=10% of the islets in the pancreas are damaged....
3.
4.
Calcinaro F, Gambelunghe G, Lafferty K
Immunol Cell Biol
. 1998 Jan;
75(5):467-71.
PMID: 9429894
Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease that is characterized by the destruction of insulin-producing beta-cells in the pancreatic islets. A single administration of CFA prevents clinical hyperglycaemia in...
5.
Desai N, Korbutt G, Barker C, Lafferty K
Diabetologia
. 1997 Nov;
40 Suppl 3:B44-9.
PMID: 9345645
No abstract available.
6.
7.
Gazda L, Charlton B, Lafferty K
J Autoimmun
. 1997 Jun;
10(3):261-70.
PMID: 9218753
IDDM in the NOD mouse is the result of a chronic autoimmune process. NOD mice are shown to express benign autoimmunity that converts to a state of malignant autoimmunity and...
8.
Lafferty K, Gazda L
Hum Immunol
. 1997 Feb;
52(2):119-26.
PMID: 9077560
The clonal selection theory of immune reactivity is based on a metaphor of self/not-self discrimination and considers self-tolerance to result from clonal deletion. There is evidence that a deletional mechanism...
9.
Coulombe M, Yang H, Guerder S, Flavell R, Lafferty K, Gill R
J Immunol
. 1996 Dec;
157(11):4790-5.
PMID: 8943380
Pancreatic islet transplantation represents a potential treatment for insulin-dependent diabetes mellitus. One approach to circumvent the requirement for recipient immune suppression is to reduce or eliminate the immunogenicity of the...
10.
Gazda L, Baxter A, Lafferty K
Immunol Cell Biol
. 1996 Oct;
74(5):401-7.
PMID: 8912002
Non-islet-antigen specific treatments have been shown to alter the natural history of insulin dependent diabetes in both the non-obese diabetic (NOD) mouse and in recently diagnosed patients. However concerns have...