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The Evident and the Hidden Factors of Vitamin D Status in Older People During COVID-19 Pandemic

Abstract

Purpose: Considering the COVID-19 pandemic, vitamin D is a target of research and speculation. Lockdown or home isolation reduces sunlight exposition and increases the risk of vitamin D deficiency. Special attention is needed for older people at risk of both severe forms of COVID-19 and vitamin D deficiency. This review aims to highlight the association of vitamin D and COVID-19 in two instances, the direct influence of vitamin D on the immune system, and the indirect risks for other vitamin D deficiency-related diseases, such as musculoskeletal properties in older persons.

Methods: We performed a narrative review.

Results: Whether vitamin D deficiency is associated with COVID-19 poor prognosis, and if vitamin D supplementation may improve the post-infection outcomes is still unclear. In any case, the pandemic generates indirect burden, such as the sequence: home isolation, low sunlight exposition, vitamin D deficiency, and fragility fractures.

Conclusion: Therefore, it is time to debate how to optimize vitamin D status in older people, especially during the COVID-19 pandemic.

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References
1.
Cameron I, Dyer S, Panagoda C, Murray G, Hill K, Cumming R . Interventions for preventing falls in older people in care facilities and hospitals. Cochrane Database Syst Rev. 2018; 9:CD005465. PMC: 6148705. DOI: 10.1002/14651858.CD005465.pub4. View

2.
Kuhn J, Trotz P, Stangl G . Prevalence of vitamin D insufficiency and evidence for disease prevention in the older population. Z Gerontol Geriatr. 2018; 51(5):567-572. DOI: 10.1007/s00391-018-1390-z. View

3.
Pereira-Santos M, Santos J, Carvalho G, Dos Santos D, Oliveira A . Epidemiology of vitamin D insufficiency and deficiency in a population in a sunny country: Geospatial meta-analysis in Brazil. Crit Rev Food Sci Nutr. 2018; 59(13):2102-2109. DOI: 10.1080/10408398.2018.1437711. View

4.
Gasmi A, Noor S, Tippairote T, Dadar M, Menzel A, Bjorklund G . Individual risk management strategy and potential therapeutic options for the COVID-19 pandemic. Clin Immunol. 2020; 215:108409. PMC: 7139252. DOI: 10.1016/j.clim.2020.108409. View

5.
Barazzoni R, Bischoff S, Breda J, Wickramasinghe K, Krznaric Z, Nitzan D . ESPEN expert statements and practical guidance for nutritional management of individuals with SARS-CoV-2 infection. Clin Nutr. 2020; 39(6):1631-1638. PMC: 7138149. DOI: 10.1016/j.clnu.2020.03.022. View