Role of MiRNAs Interference on Ovarian Functions and Premature Ovarian Failure

Overview

Journal Cell Commun Signal

Publisher Biomed Central

Specialties Biochemistry
Cell Biology

Date 2022 Dec 23

PMID 36564840

Authors

Narjes Nouri

Olduz Shareghi-Oskoue

Leili Aghebati-Maleki

Shahla Danaii

Javad Ahmadian Heris

Mohammad Sadegh Soltani-Zangbar

Amin Kamrani

Mehdi Yousefi

Affiliations

Soon will be listed here.

Abstract

Premature ovarian failure is a to some extent unknown and intricate problem with diverse causes and clinical manifestations. The lack of ovarian sex hormones presumably is effective in the occurrence of ovarian failure. Our progress in this field has been very little despite undertaken scientific research endeavors; scholars still are trying to understand the explanation of this dilemmatic medical condition. In contrast, the practice of clinical medicine has made meaningful strides in providing assurance to the women with premature ovarian insufficiency that their quality of life as well as long-term health can be optimized through timely intervention. Very recently Scientists have investigated the regulating effects of small RNA molecules on steroidogenesis apoptosis, ovulation, gonadal, and corpus luteum development of ovaries. In this literature review, we tried to talk over the mechanisms of miRNAs in regulating gene expression after transcription in the ovary. Video abstract.

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References

Baley J, Li J . MicroRNAs and ovarian function. J Ovarian Res. 2012; 5:8. PMC: 3305379. DOI: 10.1186/1757-2215-5-8. View

Richards J . Genetics of ovulation. Semin Reprod Med. 2007; 25(4):235-42. DOI: 10.1055/s-2007-980217. View

Li M, Liu Y, Wang T, Guan J, Luo Z, Chen H . Repertoire of porcine microRNAs in adult ovary and testis by deep sequencing. Int J Biol Sci. 2011; 7(7):1045-55. PMC: 3174389. DOI: 10.7150/ijbs.7.1045. View

Kuang H, Han D, Xie J, Yan Y, Li J, Ge P . Profiling of differentially expressed microRNAs in premature ovarian failure in an animal model. Gynecol Endocrinol. 2013; 30(1):57-61. DOI: 10.3109/09513590.2013.850659. View

Tripurani S, Xiao C, Salem M, Yao J . Cloning and analysis of fetal ovary microRNAs in cattle. Anim Reprod Sci. 2010; 120(1-4):16-22. DOI: 10.1016/j.anireprosci.2010.03.001. View

Zheng P, Patel B, McMenamin M, Reddy S, Paprocki A, Schramm R . The primate embryo gene expression resource: a novel resource to facilitate rapid analysis of gene expression patterns in non-human primate oocytes and preimplantation stage embryos. Biol Reprod. 2004; 70(5):1411-8. DOI: 10.1095/biolreprod.103.023788. View

Izadpanah S, Shabani P, Aghebati-Maleki A, Baghbani E, Baghbanzadeh A, Fotouhi A . Insights into the roles of miRNAs; miR-193 as one of small molecular silencer in osteosarcoma therapy. Biomed Pharmacother. 2019; 111:873-881. DOI: 10.1016/j.biopha.2018.12.106. View

Tang F, Kaneda M, OCarroll D, Hajkova P, Barton S, Sun Y . Maternal microRNAs are essential for mouse zygotic development. Genes Dev. 2007; 21(6):644-8. PMC: 1820938. DOI: 10.1101/gad.418707. View

Hung P, Liu C, Chou C, Kao S, Yang C, Chang K . miR-146a enhances the oncogenicity of oral carcinoma by concomitant targeting of the IRAK1, TRAF6 and NUMB genes. PLoS One. 2013; 8(11):e79926. PMC: 3841223. DOI: 10.1371/journal.pone.0079926. View

10.

Vo N, Klein M, Varlamova O, Keller D, Yamamoto T, Goodman R . A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A. 2005; 102(45):16426-31. PMC: 1283476. DOI: 10.1073/pnas.0508448102. View

11.

van den Hurk R, Zhao J . Formation of mammalian oocytes and their growth, differentiation and maturation within ovarian follicles. Theriogenology. 2005; 63(6):1717-51. DOI: 10.1016/j.theriogenology.2004.08.005. View

12.

Feng X, Derynck R . Specificity and versatility in tgf-beta signaling through Smads. Annu Rev Cell Dev Biol. 2005; 21:659-93. DOI: 10.1146/annurev.cellbio.21.022404.142018. View

13.

Torley K, Silveira J, Smith P, Anthony R, Veeramachaneni D, Winger Q . Expression of miRNAs in ovine fetal gonads: potential role in gonadal differentiation. Reprod Biol Endocrinol. 2011; 9:2. PMC: 3027096. DOI: 10.1186/1477-7827-9-2. View

14.

Chen X, Xie M, Liu D, Shi K . Downregulation of microRNA‑146a inhibits ovarian granulosa cell apoptosis by simultaneously targeting interleukin‑1 receptor‑associated kinase and tumor necrosis factor receptor‑associated factor 6. Mol Med Rep. 2015; 12(4):5155-62. DOI: 10.3892/mmr.2015.4036. View

15.

John B, Enright A, Aravin A, Tuschl T, Sander C, Marks D . Human MicroRNA targets. PLoS Biol. 2004; 2(11):e363. PMC: 521178. DOI: 10.1371/journal.pbio.0020363. View

16.

Wang Z, Wang Y, Yang T, Li J, Yang X . Erratum to: Study of the reparative effects of menstrual-derived stem cells on premature ovarian failure in mice. Stem Cell Res Ther. 2017; 8(1):49. PMC: 5343396. DOI: 10.1186/s13287-017-0526-1. View

17.

Lin F, Li R, Pan Z, Zhou B, Yu D, Wang X . miR-26b promotes granulosa cell apoptosis by targeting ATM during follicular atresia in porcine ovary. PLoS One. 2012; 7(6):e38640. PMC: 3380909. DOI: 10.1371/journal.pone.0038640. View

18.

Xiao G, Xia C, Yang J, Liu J, Du H, Kang X . MiR-133b regulates the expression of the Actin protein TAGLN2 during oocyte growth and maturation: a potential target for infertility therapy. PLoS One. 2014; 9(6):e100751. PMC: 4069098. DOI: 10.1371/journal.pone.0100751. View

19.

Schickel R, Boyerinas B, Park S, Peter M . MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death. Oncogene. 2008; 27(45):5959-74. DOI: 10.1038/onc.2008.274. View

20.

Yao G, Yin M, Lian J, Tian H, Liu L, Li X . MicroRNA-224 is involved in transforming growth factor-beta-mediated mouse granulosa cell proliferation and granulosa cell function by targeting Smad4. Mol Endocrinol. 2010; 24(3):540-51. PMC: 5419098. DOI: 10.1210/me.2009-0432. View