» Articles » PMID: 36200899

Toward a Data Infrastructure for the Plant Cell Atlas

Abstract

We review how a data infrastructure for the Plant Cell Atlas might be built using existing infrastructure and platforms. The Human Cell Atlas has developed an extensive infrastructure for human and mouse single cell data, while the European Bioinformatics Institute has developed a Single Cell Expression Atlas, that currently houses several plant data sets. We discuss issues related to appropriate ontologies for describing a plant single cell experiment. We imagine how such an infrastructure will enable biologists and data scientists to glean new insights into plant biology in the coming decades, as long as such data are made accessible to the community in an open manner.

Citing Articles

Building a FAIR data ecosystem for incorporating single-cell transcriptomics data into agricultural genome to phenome research.

Kapoor M, Ventura E, Walsh A, Sokolov A, George N, Kumari S Front Genet. 2024; 15:1460351.

PMID: 39678381 PMC: 11638175. DOI: 10.3389/fgene.2024.1460351.


Breaking barriers: improving time and space resolution of arbuscular mycorrhizal symbiosis with single-cell sequencing approaches.

Somoza S, Bonfante P, Giovannetti M Biol Direct. 2024; 19(1):67.

PMID: 39154166 PMC: 11330620. DOI: 10.1186/s13062-024-00501-1.


Single-Cell Sequencing Technology in Ruminant Livestock: Challenges and Opportunities.

Lyons A, Brown J, Davenport K Curr Issues Mol Biol. 2024; 46(6):5291-5306.

PMID: 38920988 PMC: 11202421. DOI: 10.3390/cimb46060316.


The Arabidopsis leaf quantitative atlas: a cellular and subcellular mapping through unified data integration.

Tolleter D, Smith E, Dupont-Thibert C, Uwizeye C, Vile D, Gloaguen P Quant Plant Biol. 2024; 5:e2.

PMID: 38572078 PMC: 10988163. DOI: 10.1017/qpb.2024.1.


Best practices for the execution, analysis, and data storage of plant single-cell/nucleus transcriptomics.

Grones C, Eekhout T, Shi D, Neumann M, Berg L, Ke Y Plant Cell. 2024; 36(4):812-828.

PMID: 38231860 PMC: 10980355. DOI: 10.1093/plcell/koae003.

References
1.
Fullgrabe A, George N, Green M, Nejad P, Aronow B, Fexova S . Guidelines for reporting single-cell RNA-seq experiments. Nat Biotechnol. 2020; 38(12):1384-1386. PMC: 9302581. DOI: 10.1038/s41587-020-00744-z. View

2.
Wilkinson M, Dumontier M, Aalbersberg I, Appleton G, Axton M, Baak A . The FAIR Guiding Principles for scientific data management and stewardship. Sci Data. 2016; 3:160018. PMC: 4792175. DOI: 10.1038/sdata.2016.18. View

3.
Jha S, Borowsky A, Cole B, Fahlgren N, Farmer A, Huang S . Vision, challenges and opportunities for a Plant Cell Atlas. Elife. 2021; 10. PMC: 8423441. DOI: 10.7554/eLife.66877. View

4.
Cleary A, Farmer A . Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny. Bioinformatics. 2017; 34(9):1562-1564. PMC: 5925771. DOI: 10.1093/bioinformatics/btx757. View

5.
Jores T, Tonnies J, Wrightsman T, Buckler E, Cuperus J, Fields S . Synthetic promoter designs enabled by a comprehensive analysis of plant core promoters. Nat Plants. 2021; 7(6):842-855. PMC: 10246763. DOI: 10.1038/s41477-021-00932-y. View