Myocardial T2* Imaging at 3T and 1.5T: A Pilot Study with Phantom and Normal Myocardium

Overview

Journal J Cardiovasc Dev Dis

Specialty Cardiology & Vascular Diseases

Date 2022 Aug 25

PMID 36005435

Authors

Suyon Chang

Jinho Park

Young-Joong Yang

Kyongmin Sarah Beck

Pan Ki Kim

Byoung Wook Choi

Jung Im Jung

Affiliations

Soon will be listed here.

Abstract

Background: Myocardial T2* mapping at 1.5T remains the gold standard, but the use of 3T scanners is increasing. We aimed to determine the conversion equations in different scanners with clinically available, vendor-provided T2* mapping sequences using a phantom and evaluated the feasibility of the phantom-based conversion method.

Methods: T2* of a phantom with FeCl (five samples, 3.53-20.09 mM) were measured with 1.5T (MR-A1) and 3T scanners (MR-A2, A3, B), and the site-specific equation was determined. T2* was measured in the interventricular septum of three healthy volunteers at 1.5T (T2*, MR-A1) and 3T (T2*, MR-B). T2* was converted based on the equation derived from the phantom (T2*).

Results: R2* at 1.5T and 3T showed linear association, but a different relationship was observed according to the scanners (MR-A2, R2* = 0.76 × R2* - 2.23, = 0.999; MR-A3, R2* = 0.95 × R2*3.0T - 34.28, = 0.973; MR-B, R2* = 0.76 × R2* - 3.02, = 0.999). In the normal myocardium, T2* and T2* showed no significant difference (35.5 ± 3.5 vs. 34.5 ± 1.2, = 0.340). The mean squared error between T2* and T2* was 16.33, and Bland-Altman plots revealed a small bias (-0.94, 95% limits of agreement: -8.86-6.99).

Conclusions: a phantom-based, site-specific equation can be utilized to estimate T2* values at 1.5T in centers where only 3T scanners are available.

Citing Articles

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