A Lineage-specific Exo70 is Required for Receptor Kinase-mediated Immunity in Barley

Overview

Journal Sci Adv

Specialties Biology
Science

Date 2022 Jul 20

PMID 35857460

Authors

Samuel Holden

Molly Bergum

Phon Green

Jan Bettgenhaeuser

Inmaculada Hernandez-Pinzon

Anupriya Thind

Shaun Clare

James M Russell

Amelia Hubbard

Jodi Taylor

Matthew Smoker

Matthew Gardiner

Laura Civolani

Francesco Cosenza

Serena Rosignoli

Roxana Strugala

Istvan Molnar

Hana Simkova

Jaroslav Dolezel

Ulrich Schaffrath

Matthew Barrett

Silvio Salvi

Matthew J Moscou

Affiliations

Soon will be listed here.

Abstract

In the evolution of land plants, the plant immune system has experienced expansion in immune receptor and signaling pathways. Lineage-specific expansions have been observed in diverse gene families that are potentially involved in immunity but lack causal association. Here, we show that -mediated resistance in barley to the pathogen f. sp. (wheat stripe rust) is conferred by a genetic module: and , which are together necessary and sufficient. encodes a leucine-rich repeat receptor kinase and is the ortholog of rice , and Exo70FX12 belongs to the Poales-specific Exo70FX clade. The Exo70FX clade emerged after the divergence of the Bromeliaceae and Poaceae and comprises from 2 to 75 members in sequenced grasses. These results demonstrate the requirement of a lineage-specific Exo70FX12 in Pur1-mediated immunity and suggest that the Exo70FX clade may have evolved a specialized role in receptor kinase signaling.

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