Hana Simkova
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Explore the profile of Hana Simkova including associated specialties, affiliations and a list of published articles.
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Articles
103
Citations
3606
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Recent Articles
1.
Moraga C, Branco C, Rougemont Q, Jedlicka P, Mendoza-Galindo E, Veltsos P, et al.
Science
. 2025 Feb;
387(6734):630-636.
PMID: 39913565
In many species with sex chromosomes, the Y is a tiny chromosome. However, the dioecious plant has a giant ~550-megabase Y chromosome, which has remained unsequenced so far. We used...
2.
Guo W, Schreiber M, Marosi V, Bagnaresi P, Jorgensen M, Braune K, et al.
Nat Genet
. 2025 Feb;
57(2):441-450.
PMID: 39901014
A pan-transcriptome describes the transcriptional and post-transcriptional consequences of genome diversity from multiple individuals within a species. We developed a barley pan-transcriptome using 20 inbred genotypes representing domesticated barley diversity...
3.
Chen J, Bartos J, Boudichevskaia A, Voigt A, Rabanus-Wallace M, Dreissig S, et al.
Nat Commun
. 2024 Nov;
15(1):9686.
PMID: 39516474
The genomes of many plants, animals, and fungi frequently comprise dispensable B chromosomes that rely upon various chromosomal drive mechanisms to counteract the tendency of non-essential genetic elements to be...
4.
Heuberger M, Bernasconi Z, Said M, Jung E, Herren G, Widrig V, et al.
Theor Appl Genet
. 2024 Sep;
137(10):236.
PMID: 39340575
This study highlights the agronomic potential of rare introgressions, as demonstrated by a major QTL for powdery mildew resistance on chromosome 7D. It further shows evidence for inter-homoeologue recombination in...
5.
Simkova H, Camara A, Mascher M
J Exp Bot
. 2024 Mar;
75(17):5357-5365.
PMID: 38430521
The invention of chromosome conformation capture (3C) techniques, in particular the key method Hi-C providing genome-wide information about chromatin contacts, revolutionized the way we study the three-dimensional organization of the...
6.
Pavlu S, Nikumbh S, Kovacik M, An T, Lenhard B, Simkova H, et al.
Comput Struct Biotechnol J
. 2024 Jan;
23:264-277.
PMID: 38173877
Precise localization and dissection of gene promoters are key to understanding transcriptional gene regulation and to successful bioengineering applications. The core RNA polymerase II initiation machinery is highly conserved among...
7.
Brabham H, Gomez De la Cruz D, Were V, Shimizu M, Saitoh H, Hernandez-Pinzon I, et al.
Plant Cell
. 2023 Oct;
36(2):447-470.
PMID: 37820736
Plant nucleotide-binding leucine-rich repeat (NLRs) immune receptors directly or indirectly recognize pathogen-secreted effector molecules to initiate plant defense. Recognition of multiple pathogens by a single NLR is rare and usually...
8.
Simkova H, Tulpova Z, Capal P
Methods Mol Biol
. 2023 Jun;
2672:465-483.
PMID: 37335494
Optical mapping-a technique that visualizes short sequence motives along DNA molecules of hundred kilobases to megabase in size-has found an important place in genome research. It is widely used to...
9.
Kubalova I, Camara A, Capal P, Beseda T, Rouillard J, Krause G, et al.
Nucleic Acids Res
. 2023 Mar;
51(6):2641-2654.
PMID: 36864547
Chromatids of mitotic chromosomes were suggested to coil into a helix in early cytological studies and this assumption was recently supported by chromosome conformation capture (3C) sequencing. Still, direct differential...
10.
Hofstatter P, Thangavel G, Lux T, Neumann P, Vondrak T, Novak P, et al.
Cell
. 2022 Aug;
185(17):3153-3168.e18.
PMID: 35926507
The centromere represents a single region in most eukaryotic chromosomes. However, several plant and animal lineages assemble holocentromeres along the entire chromosome length. Here, we compare genome organization and evolution...