Divergent Synthesis of Flavones and Flavanones from 2'-hydroxydihydrochalcones Palladium(ii)-catalyzed Oxidative Cyclization

Overview

Journal RSC Adv

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2022 Apr 15

PMID 35423945

Authors

Seung Hwan Son

Yang Yil Cho

Hyung-Seok Yoo

Soo Jin Lee

Young Min Kim

Hyu Jeong Jang

Dong Hwan Kim

Jeong-Won Shin

Nam-Jung Kim

Affiliations

Soon will be listed here.

Abstract

Divergent and versatile synthetic routes to flavones and flavanones efficient Pd(ii) catalysis are disclosed. These Pd(ii) catalyses expediently provide a variety of flavones and flavanones from 2'-hydroxydihydrochalcones as common intermediates, depending on oxidants and additives, discriminate oxidative cyclization sequences involving dehydrogenation, respectively, in a highly atom-economic manner.

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