Hyung-Seok Yoo
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Explore the profile of Hyung-Seok Yoo including associated specialties, affiliations and a list of published articles.
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16
Citations
76
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Recent Articles
1.
Yoo H, Yoon Y, Shin J, Choi S, Son S, Jang Y, et al.
Int Immunopharmacol
. 2025 Jan;
148:114175.
PMID: 39889413
In the present study, we developed and synthesized novel hydrangenol derivatives and featured their anti-inflammatory activities. Especially, a synthetic derivative 11 (compound 11), which possesses the 4H-1-benzopyran-4-one moiety, 5-hydroxyl group...
2.
Yoo H, Shin J, Jang Y, Yang Y, Son S, Won H, et al.
J Org Chem
. 2024 Feb;
89(5):3102-3110.
PMID: 38364274
An approach to 2,3-benzotropone from 1-benzosuberone via palladium(II)-catalyzed aerobic dehydrogenation was developed. This method first provided a catalytic route to various 2,3-benzotropones from their corresponding 1-benzosuberones in good yields. In...
3.
Yeon N, Cho J, Yoo H, Jeon S, Yi C, Jung M, et al.
Life Sci
. 2024 Jan;
340:122424.
PMID: 38242497
Inflammatory Bowel Disease (IBD) is a chronic and relapsing inflammatory condition characterized by severe symptoms such as diarrhea, fatigue, and weight loss. Growing evidence underscores the direct involvement of the...
4.
Lee H, Shin J, Chung K, Kim J, Jung S, Yoo H, et al.
Phytomedicine
. 2023 Jan;
109:154553.
PMID: 36610153
Background: We previously reported the potential inhibitory activity of 3',4'-dihydroxyflavone (DHF) on nitric oxide (NO) and prostaglandin E (PGE) production in lipopolysaccharide (LPS)-stimulated macrophages. Purpose: We investigated the underlying molecular...
5.
Jang Y, Yang Y, Son S, Yoo H, Shin J, Won H, et al.
Org Lett
. 2022 Dec;
24(50):9216-9221.
PMID: 36512443
In this study, an unprecedented approach to the xanthone scaffold from cyclohexyl(2-hydroxyphenyl)methanone via dehydrogenative cyclization and a successive aromatization cascade is reported. This methodology affords a novel route to the...
6.
Son S, Cho Y, Yoo H, Lee S, Kim Y, Jang H, et al.
RSC Adv
. 2022 Apr;
11(23):14000-14006.
PMID: 35423945
Divergent and versatile synthetic routes to flavones and flavanones efficient Pd(ii) catalysis are disclosed. These Pd(ii) catalyses expediently provide a variety of flavones and flavanones from 2'-hydroxydihydrochalcones as common intermediates,...
7.
Son S, Shin J, Won H, Yoo H, Cho Y, Kim S, et al.
Org Lett
. 2021 Sep;
23(19):7467-7471.
PMID: 34523938
Facile construction of a -(indol-3-yl)phenol framework with a wide substrate scope (a total of 25 compounds) via a palladium(II)-catalyzed oxidative Heck reaction and dehydrogenative aromatization in a one-step sequence is...
8.
Yoo H, Yang Y, Kim S, Son S, Jang Y, Shin J, et al.
Chem Asian J
. 2021 Sep;
16(21):3469-3475.
PMID: 34494376
Aromatic N-heterocycle-fused scaffolds such as indoles and quinolines are important core structures found in various bioactive natural products and synthetic compounds. Recently, various dehydrogenation methods with the help of alkoxides,...
9.
Son S, Do J, Yoo J, Lee H, Kim N, Yoo H, et al.
Bioorg Chem
. 2021 Jun;
113:105022.
PMID: 34098397
In this study, polyhydroxyisoflavones that directly prevent the aggregation of both amyloid β (Aβ) and tau were expediently synthesized via divergent Pd(0)-catalyzed Suzuki-Miyaura coupling and then biologically evaluated. By preliminary...
10.
Kim G, Song C, Yang Y, Lee N, Yoo H, Son S, et al.
Molecules
. 2021 Apr;
26(9).
PMID: 33926033
A series of PROTACs (PROteolysis-TArgeting Chimeras) consisting of bicalutamide analogs and thalidomides were designed, synthesized, and biologically evaluated as novel androgen receptor (AR) degraders. In particular, we found that PROTAC...