A Versatile Approach to Flavones Via a One-pot Pd(II)-catalyzed Dehydrogenation/oxidative Boron-Heck Coupling Sequence of Chromanones

Overview

Journal Org Biomol Chem

Publisher Royal Society of Chemistry

Specialties Biochemistry
Chemistry

Date 2015 Nov 24

PMID 26592753

Citations 7

Authors

Jun Lee

Jihyun Yu

Seung Hwan Son

Jinyuk Heo

Taelim Kim

Ji-Young An

Kyung-Soo Inn

Nam-Jung Kim

Affiliations

Soon will be listed here.

Abstract

A variety of flavones were expediently synthesized from readily accessible chromanones via a one-pot sequence involving Pd(II)-catalyzed dehydrogenation and oxidative boron-Heck coupling with arylboronic acid pinacol esters. In particular, the use of arylboronic acid pinacol esters was found to significantly improve the yield of the reaction.

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