PubChem Protein, Gene, Pathway, and Taxonomy Data Collections: Bridging Biology and Chemistry Through Target-Centric Views of PubChem Data

Overview

Journal J Mol Biol

Publisher Elsevier

Specialties Microbiology
Molecular Biology

Date 2022 Mar 1

PMID 35227770

Authors

Sunghwan Kim

Tiejun Cheng

Siqian He

Paul A Thiessen

Qingliang Li

Asta Gindulyte

Evan E Bolton

Affiliations

Soon will be listed here.

Abstract

PubChem (https://pubchem.ncbi.nlm.nih.gov) is a public chemical database at the U.S. National Institutes of Health. Visited by millions of users every month, it plays a role as a key chemical information resource for biomedical research communities. Data in PubChem is from hundreds of contributors and organized into multiple collections by record type. Among these are the Protein, Gene, Pathway, and Taxonomy data collections. Records in these collections contain information on chemicals related to a given biological target (i.e., protein, gene, pathway, or taxon), helping users to analyze and interpret the biological activity data of molecules. In addition, annotations about the biological targets are collected from authoritative or curated data sources and integrated into the four collections. The content can be programmatically accessed through PubChem's web service interfaces (including PUG View). A machine-readable representation of this content is also provided within PubChemRDF.

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