Detection of Anti- Antibodies in Humans: An Update from Pakistan

Overview

Journal Pathogens

Date 2022 Jan 21

PMID 35055977

Authors

Huma Khan

Haroon Ahmed

Muhammad Sohail Afzal

Usman Ayub Awan

Muhammad Khurram

Sami Simsek

Jianping Cao

Affiliations

Soon will be listed here.

Abstract

Human cystic echinococcosis (CE) is a zoonotic disease caused by the larval stage of sensu lato that causes economic losses by affecting livestock and also poses a public health threat worldwide. The present study is the first retrospective report on the seroprevalence of anti- antibodies in humans in Pakistan. The study used data from 93 blood analysis reports of patients suspected of having CE from different medical centers in Lahore, Pakistan. Out of 93 sera samples, 20 (21.5%) were seropositive, and higher seropositivity (17.2%) was recorded with the indirect hemagglutination test (IHA) than with enzyme-linked immunosorbent assay (ELISA). The findings indicated that age, gender, and year had no significant relationship with the seropositivity of CE. The current study provides directions towards the management of the disease in the near future in Pakistan.

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