The Seroprevalence of Human Cystic Echinococcosis in Iran: A Systematic Review and Meta-Analysis Study

Overview

Journal J Parasitol Res

Publisher Wiley

Specialty Parasitology

Date 2016 Nov 11

PMID 27830083

Citations 16

Authors

Reza Shafiei

Saeed Hosseini Teshnizi

Kurosh Kalantar

Maryam Gholami

Golnush Mirzaee

Fatemeh Mirzaee

Affiliations

Soon will be listed here.

Abstract

Human cystic echinococcosis (HCE), a zoonotic infection of the larval stage of , has high effect on public health in human population all around the world. Iran is one of the most important endemic areas in the Middle East. This systematic review and meta-analysis was performed to evaluate the seroprevalence of HCE in Iranian population. An electronic search for articles from 1985 until April 2015 was performed using data bases PubMed, Scopus, Google Scholar, Magiran, IranMedex, Iran Doc, and Scientific Information Database (SID) both in English and in Persian. A random-effects meta-analysis was used to combine results from individual studies. The information was analyzed by STATA version 11.1. A total of 33 articles met our eligibility criteria and were included in a meta-analysis. The pooled estimate of the prevalence of HCE based on random-effects model was estimated 6.0% (95% CI: 4.0%, 7.0%). The prevalence of the disease significantly increased with age and prevalence rate in males was significantly lower than females ( < 0.001). The using of CIE or CCIEP method was also significantly greater than the other methods ( < 0.001). There was a publication bias in prevalence of studies. HCE is highly prevalent in Iran. Public education for preventive strategies and finally reducing transmission of the parasite and infection in population is needed.

Citing Articles

Status of human cystic echinococcosis based on hospital records in Mazandaran Province: A first registry-based evidence.

Tabaripour R, Sharifpour A, Fakhar M, Asadi S, Esmaeili Reykandeh S, Montazeri M Parasite Epidemiol Control. 2023; 22:e00314.

PMID: 37457119 PMC: 10344820. DOI: 10.1016/j.parepi.2023.e00314.

Hydatid Disease: A Pictorial Review of Uncommon Locations.

Khalili N, Iranpour P, Khalili N, Haseli S Iran J Med Sci. 2023; 48(2):118-129.

PMID: 36895460 PMC: 9989246. DOI: 10.30476/IJMS.2022.93123.2442.

Efficacy of Preoperative Albendazole on Protoscoleces Viability in Hydatid Cyst of the Liver.

Vahidirad A, Mansouri M, Shamshirian A, Berenji F, Motie M Iran J Parasitol. 2023; 17(4):483-487.

PMID: 36694569 PMC: 9825706. DOI: 10.18502/ijpa.v17i4.11274.

Africa-wide meta-analysis on the prevalence and distribution of human cystic echinococcosis and canine Echinococcus granulosus infections.

Karshima S, Ahmed M, Adamu N, Magaji A, Zakariah M, Mohammed K Parasit Vectors. 2022; 15(1):357.

PMID: 36199100 PMC: 9535855. DOI: 10.1186/s13071-022-05474-6.

Detection of Anti- Antibodies in Humans: An Update from Pakistan.

Khan H, Ahmed H, Afzal M, Awan U, Khurram M, Simsek S Pathogens. 2022; 11(1).

PMID: 35055977 PMC: 8781053. DOI: 10.3390/pathogens11010029.

References

Zibaei M, Azargoon A, Ataie-Khorasgani M, Ghanadi K, Sadjjadi S . The serological study of cystic echinococcosis and assessment of surgical cases during 5 years (2007-2011) in Khorram Abad, Iran. Niger J Clin Pract. 2013; 16(2):221-5. DOI: 10.4103/1119-3077.110156. View

Sadjjadi S . Present situation of echinococcosis in the Middle East and Arabic North Africa. Parasitol Int. 2005; 55 Suppl:S197-202. DOI: 10.1016/j.parint.2005.11.030. View

Fasihi Harandi M, Hobbs R, Adams P, Mobedi I, Morgan-Ryan U, Thompson R . Molecular and morphological characterization of Echinococcus granulosus of human and animal origin in Iran. Parasitology. 2002; 125(Pt 4):367-73. DOI: 10.1017/s0031182002002172. View

Moro P, Schantz P . Echinococcosis: a review. Int J Infect Dis. 2008; 13(2):125-33. DOI: 10.1016/j.ijid.2008.03.037. View

Hezarjaribi H, Fakhar M, Shokri A, Teshnizi S, Sadough A, Taghavi M . Trichomonas vaginalis infection among Iranian general population of women: a systematic review and meta-analysis. Parasitol Res. 2015; 114(4):1291-300. DOI: 10.1007/s00436-015-4393-3. View

Ilbeigi P, Mohebali M, Kia E, Saber-Inasab M, Aryaeipour M, Bizhani N . Seroepidemiology of Human Hydatidosis Using AgB-ELISA Test in Isfahan City and Suburb Areas, Isfahan Province, Central Iran. Iran J Public Health. 2015; 44(9):1219-24. PMC: 4645779. View

Rafiei A, Hemadi A, Maraghi S, Kaikhaei B, Craig P . Human cystic echinococcosis in nomads of south-west Islamic Republic of Iran. East Mediterr Health J. 2007; 13(1):41-8. View

Heidari Z, Mohebali M, Zarei Z, Aryayipour M, Eshraghian M, Kia E . Seroepidemiological study of human hydatidosis in meshkinshahr district, ardabil province, iran. Iran J Parasitol. 2012; 6(3):19-25. PMC: 3279891. View

Sarkari B, Rezaei Z . Immunodiagnosis of human hydatid disease: Where do we stand?. World J Methodol. 2015; 5(4):185-95. PMC: 4686415. DOI: 10.5662/wjm.v5.i4.185. View

10.

Asghari M, Mohebali M, Kia E, Farahnak A, Aryaeipour M, Asadian S . Seroepidemiology of Human Hydatidosis Using AgB-ELISA Test in Arak, Central Iran. Iran J Public Health. 2013; 42(4):391-6. PMC: 3684725. View

11.

Harandi M, Budke C, Rostami S . The monetary burden of cystic echinococcosis in Iran. PLoS Negl Trop Dis. 2012; 6(11):e1915. PMC: 3510083. DOI: 10.1371/journal.pntd.0001915. View

12.

Harandi M, Moazezi S, Saba M, Grimm F, Kamyabi H, Sheikhzadeh F . Sonographical and serological survey of human cystic echinococcosis and analysis of risk factors associated with seroconversion in rural communities of Kerman, Iran. Zoonoses Public Health. 2011; 58(8):582-8. DOI: 10.1111/j.1863-2378.2011.01407.x. View

13.

Dalimi A, Motamedi G, Hosseini M, Mohammadian B, Malaki H, Ghamari Z . Echinococcosis/hydatidosis in western Iran. Vet Parasitol. 2002; 105(2):161-71. DOI: 10.1016/s0304-4017(02)00005-5. View

14.

Torgerson P, Deplazes P . Echinococcosis: diagnosis and diagnostic interpretation in population studies. Trends Parasitol. 2009; 25(4):164-70. DOI: 10.1016/j.pt.2008.12.008. View

15.

Rahimi M, Daryani A, Sarvi S, Shokri A, Ahmadpour E, Teshnizi S . Cats and Toxoplasma gondii: A systematic review and meta-analysis in Iran. Onderstepoort J Vet Res. 2015; 82(1):e1-e10. PMC: 6238687. DOI: 10.4102/ojvr.v82i1.823. View

16.

Rokni M . The present status of human helminthic diseases in Iran. Ann Trop Med Parasitol. 2008; 102(4):283-95. DOI: 10.1179/136485908X300805. View

17.

Zhang W, Wen H, Li J, Lin R, McManus D . Immunology and immunodiagnosis of cystic echinococcosis: an update. Clin Dev Immunol. 2012; 2012:101895. PMC: 3253442. DOI: 10.1155/2012/101895. View

18.

Sadjjadi S, Ardehali S, Noman-Pour B, Kumar V, Izadpanah A . Diagnosis of cystic echinococcosis: ultrasound imaging or countercurrent immunoelectrophoresis?. East Mediterr Health J. 2004; 7(6):907-11. View

19.

Sarkari B, Sadjjadi S, Beheshtian M, Aghaee M, Sedaghat F . Human cystic echinococcosis in Yasuj District in Southwest of Iran: an epidemiological study of seroprevalence and surgical cases over a ten-year period. Zoonoses Public Health. 2009; 57(2):146-50. DOI: 10.1111/j.1863-2378.2008.01200.x. View

20.

Rakhshanpour A, Fasihi Harandi M, Moazezi S, Rahimi M, Mohebali M, Mowlavi G . Seroprevalence of human hydatidosis using ELISA method in qom province, central iran. Iran J Parasitol. 2012; 7(3):10-5. PMC: 3469166. View