Design of the Pilot, Proof of Concept REMOTE-COVID Trial: Remote Monitoring Use in Suspected Cases of COVID-19 (SARS-CoV-2)

Overview

Journal Pilot Feasibility Stud

Publisher Biomed Central

Date 2021 Mar 6

PMID 33673868

Citations 9

Authors

Fahad Mujtaba Iqbal

Meera Joshi

Gary Davies

Sadia Khan

Hutan Ashrafian

Ara Darzi

Affiliations

Soon will be listed here.

Abstract

Background: The outbreak of SARS-CoV-2 (coronavirus, COVID-19), declared a pandemic by the World Health Organization (WHO), is a global health problem with ever-increasing attributed deaths. Vital sign trends are routinely used to monitor patients with changes in these parameters often preceding an adverse event. Wearable sensors can measure vital signs continuously (e.g. heart rate, respiratory rate, temperature) remotely and can be utilised to recognise early clinical deterioration.

Methods: We describe the protocol for a pilot, proof-of-concept, observational study to be conducted in an engineered hotel near London airports, UK. The study is set to continue for the duration of the pandemic. Individuals arriving to London with mild symptoms suggestive of COVID-19 or returning from high-risk areas requiring quarantine, as recommended by the Public Health England, or healthcare professionals with symptoms suggestive of COVID-19 unable to isolate at home will be eligible for a wearable patch to be applied for the duration of their stay. Notifications will be generated should deterioration be detected through the sensor and displayed on a central monitoring hub viewed by nursing staff, allowing for trend deterioration to be noted. The primary objective is to determine the feasibility of remote monitoring systems in detecting clinical deterioration for quarantined individuals in a hotel.

Discussion: This trial should prove the feasibility of a rapidly implemented model of healthcare delivery through remote monitoring during a global pandemic at a hotel, acting as an extension to a healthcare trust. Potential benefits would include reducing infection risk of COVID-19 to healthcare staff, with earlier recognition of clinical deterioration through ambulatory, continuous, remote monitoring using a discrete wearable sensor. We hope our results can power future, robust randomised trials.

Trial Registration: ClinicalTrials.gov Identifier: NCT04337489 .

Citing Articles

Remote Patient Monitoring at Home in Patients With COVID-19: Narrative Review.

Cornelis J, Christiaens W, de Meester C, Mistiaen P JMIR Nurs. 2024; 7:e44580.

PMID: 39287362 PMC: 11615560. DOI: 10.2196/44580.

Analysis and clinical determinants of post-COVID-19 syndrome in the Lombardy region: evidence from a longitudinal cohort study.

Borgonovo F, Lovaglio P, Mariani C, Berta P, Cossu M, Rizzardini G BMJ Open. 2024; 14(2):e075185.

PMID: 38320835 PMC: 10860093. DOI: 10.1136/bmjopen-2023-075185.

Acceptance and User Experiences of a Wearable Device for the Management of Hospitalized Patients in COVID-19-Designated Wards in Ho Chi Minh City, Vietnam: Action Learning Project.

Luu A, Nguyen T, Cao V, Ha T, Chung L, Truong T JMIR Hum Factors. 2024; 11:e44619.

PMID: 38180799 PMC: 10773555. DOI: 10.2196/44619.

A survey of COVID-19 detection and prediction approaches using mobile devices, AI, and telemedicine.

Shen J, Ghatti S, Levkov N, Shen H, Sen T, Rheuban K Front Artif Intell. 2022; 5:1034732.

PMID: 36530356 PMC: 9755752. DOI: 10.3389/frai.2022.1034732.

Respinos: A Portable Device for Remote Vital Signs Monitoring of COVID-19 Patients.

Adiono T, Ahmadi N, Saraswati C, Aditya Y, Yudhanto Y, Aziz A IEEE Trans Biomed Circuits Syst. 2022; 16(5):947-961.

PMID: 36067112 PMC: 9906646. DOI: 10.1109/TBCAS.2022.3204632.

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