The Current Status and Further Prospects for Lung Magnetic Resonance Imaging in Pediatric Radiology

Overview

Journal Pediatr Radiol

Specialty Pediatrics

Date 2020 Jan 31

PMID 31996938

Citations 22

Authors

Franz Wolfgang Hirsch

Ina Sorge

Jens Vogel-Claussen

Christian Roth

Daniel Grafe

Anne Pats

Andreas Voskrebenzev

Rebecca Marie Anders

Affiliations

Soon will be listed here.

Abstract

Lung MRI makes it possible to replace up to 90% of CT examinations with radiation-free magnetic resonance diagnostics of the lungs without suffering any diagnostic loss. The individual radiation exposure can thus be relevantly reduced. This applies in particular to children who repeatedly require sectional imaging of the lung, e.g., in tumor surveillance or in chronic lung diseases such as cystic fibrosis. In this paper we discuss various factors that favor the establishment of lung MRI in the clinical setting. Among the many sequences proposed for lung imaging, respiration-triggered T2-W turbo spin-echo (TSE) sequences have been established as a good standard for children. Additional sequences are mostly dispensable. The most important pulmonary findings are demonstrated here in the form of a detailed pictorial essay. T1-weighted gradient echo sequences with ultrashort echo time are a new option. These sequences anticipate signal loss in the lung and deliver CT-like images with high spatial resolution. When using self-gated T1-W ultrashort echo time 3-D sequences that acquire iso-voxel geometry in the sub-millimeter range, secondary reconstructions are possible.

Citing Articles

Practical strategies to improve MRI operations and workflow in pediatric radiology.

Calixto C, Gee M Pediatr Radiol. 2024; 55(1):12-23.

PMID: 39704827 DOI: 10.1007/s00247-024-06114-0.

A review on functional lung avoidance radiotherapy plan for lung cancer.

Yu J, Tang X, Lei Y, Zhang Z, Li B, Bai H Front Oncol. 2024; 14:1429837.

PMID: 39703855 PMC: 11656049. DOI: 10.3389/fonc.2024.1429837.

A bootstrapping residuals approach to determine the error in quantitative functional lung imaging.

Slawig A, Weng A, Veldhoen S, Kostler H Magn Reson Med. 2024; 93(4):1484-1498.

PMID: 39552181 PMC: 11782724. DOI: 10.1002/mrm.30367.

Acute Respiratory Failure in Children: A Clinical Update on Diagnosis.

Panetti B, Bucci I, Di Ludovico A, Pellegrino G, Di Filippo P, Di Pillo S Children (Basel). 2024; 11(10).

PMID: 39457197 PMC: 11506303. DOI: 10.3390/children11101232.

[Congenital diaphragmatic hernia : Imaging-from diagnosis to aftercare].

Thater G, Appelhaus S, Schoenberg S, Weis M Radiologie (Heidelb). 2024; 64(5):366-372.

PMID: 38587632 DOI: 10.1007/s00117-024-01289-x.

References

Togao O, Tsuji R, Ohno Y, Dimitrov I, Takahashi M . Ultrashort echo time (UTE) MRI of the lung: assessment of tissue density in the lung parenchyma. Magn Reson Med. 2010; 64(5):1491-8. DOI: 10.1002/mrm.22521. View

Zirpoli S, Munari A, Primolevo A, Scarabello M, Costanzo S, Farolfi A . Agreement between magnetic resonance imaging and computed tomography in the postnatal evaluation of congenital lung malformations: a pilot study. Eur Radiol. 2019; 29(9):4544-4554. DOI: 10.1007/s00330-019-06042-w. View

Wielputz M, Triphan S, Ohno Y, Jobst B, Kauczor H . Outracing Lung Signal Decay - Potential of Ultrashort Echo Time MRI. Rofo. 2018; 191(5):415-423. DOI: 10.1055/a-0715-2246. View

Leutz-Schmidt P, Eichinger M, Stahl M, Sommerburg O, Biederer J, Kauczor H . Ten years of chest MRI for patients with cystic fibrosis : Translation from the bench to clinical routine. Radiologe. 2019; 59(Suppl 1):10-20. DOI: 10.1007/s00117-019-0553-2. View

Liszewski M, Gorkem S, Sodhi K, Lee E . Lung magnetic resonance imaging for pneumonia in children. Pediatr Radiol. 2017; 47(11):1420-1430. DOI: 10.1007/s00247-017-3865-2. View

Delacoste J, Dournes G, Dunet V, Ogna A, Noirez L, Simons J . Ultrashort echo time imaging of the lungs under high-frequency noninvasive ventilation: A new approach to lung imaging. J Magn Reson Imaging. 2019; 50(6):1789-1797. PMC: 6900075. DOI: 10.1002/jmri.26808. View

Voskrebenzev A, Gutberlet M, Klimes F, Kaireit T, Schonfeld C, Rotarmel A . Feasibility of quantitative regional ventilation and perfusion mapping with phase-resolved functional lung (PREFUL) MRI in healthy volunteers and COPD, CTEPH, and CF patients. Magn Reson Med. 2017; 79(4):2306-2314. DOI: 10.1002/mrm.26893. View

Zeng J, Liu Z, Shen G, Zhang Y, Li L, Wu Z . MRI evaluation of pulmonary lesions and lung tissue changes induced by tuberculosis. Int J Infect Dis. 2019; 82:138-146. DOI: 10.1016/j.ijid.2019.03.004. View

Torres L, Kammerman J, Hahn A, Zha W, Nagle S, Johnson K . "Structure-Function Imaging of Lung Disease Using Ultrashort Echo Time MRI". Acad Radiol. 2019; 26(3):431-441. PMC: 7032698. DOI: 10.1016/j.acra.2018.12.007. View

10.

Kaireit T, Sorrentino S, Renne J, Schoenfeld C, Voskrebenzev A, Gutberlet M . Functional lung MRI for regional monitoring of patients with cystic fibrosis. PLoS One. 2017; 12(12):e0187483. PMC: 5720731. DOI: 10.1371/journal.pone.0187483. View

11.

Ohno Y, Koyama H, Lee H, Miura S, Yoshikawa T, Sugimura K . Contrast-enhanced CT- and MRI-based perfusion assessment for pulmonary diseases: basics and clinical applications. Diagn Interv Radiol. 2016; 22(5):407-21. PMC: 5019844. DOI: 10.5152/dir.2016.16123. View

12.

Ohno Y, Koyama H, Yoshikawa T, Seki S, Takenaka D, Yui M . Pulmonary high-resolution ultrashort TE MR imaging: Comparison with thin-section standard- and low-dose computed tomography for the assessment of pulmonary parenchyma diseases. J Magn Reson Imaging. 2015; 43(2):512-32. DOI: 10.1002/jmri.25008. View

13.

Nguyen A, Perez-Rovira A, Wielopolski P, Hernandez Tamames J, Duijts L, De Bruijne M . Technical challenges of quantitative chest MRI data analysis in a large cohort pediatric study. Eur Radiol. 2018; 29(6):2770-2782. PMC: 6510873. DOI: 10.1007/s00330-018-5863-7. View

14.

Hirsch W, Sorge I, Krohmer S, Weber D, Meier K, Till H . MRI of the lungs in children. Eur J Radiol. 2008; 68(2):278-88. DOI: 10.1016/j.ejrad.2008.05.017. View

15.

Mon R, Johnson K, Ladino-Torres M, Heider A, Mychaliska G, Treadwell M . Diagnostic accuracy of imaging studies in congenital lung malformations. Arch Dis Child Fetal Neonatal Ed. 2018; 104(4):F372-F377. DOI: 10.1136/archdischild-2018-314979. View

16.

Alsady T, Voskrebenzev A, Greer M, Becker L, Kaireit T, Welte T . MRI-derived regional flow-volume loop parameters detect early-stage chronic lung allograft dysfunction. J Magn Reson Imaging. 2019; 50(6):1873-1882. DOI: 10.1002/jmri.26799. View

17.

Biederer J, Beer M, Hirsch W, Wild J, Fabel M, Puderbach M . MRI of the lung (2/3). Why … when … how?. Insights Imaging. 2012; 3(4):355-71. PMC: 3481084. DOI: 10.1007/s13244-011-0146-8. View

18.

Cieszanowski A, Lisowska A, Dabrowska M, Korczynski P, Zukowska M, Grudzinski I . MR Imaging of Pulmonary Nodules: Detection Rate and Accuracy of Size Estimation in Comparison to Computed Tomography. PLoS One. 2016; 11(6):e0156272. PMC: 4892605. DOI: 10.1371/journal.pone.0156272. View

19.

Nyilas S, Bauman G, Sommer G, Stranzinger E, Pusterla O, Frey U . Novel magnetic resonance technique for functional imaging of cystic fibrosis lung disease. Eur Respir J. 2017; 50(6). DOI: 10.1183/13993003.01464-2017. View

20.

Ohno Y, Kauczor H, Hatabu H, Seo J, van Beek E . MRI for solitary pulmonary nodule and mass assessment: Current state of the art. J Magn Reson Imaging. 2018; 47(6):1437-1458. DOI: 10.1002/jmri.26009. View