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European Guideline for Imaging in Paediatric and Adolescent Rhabdomyosarcoma - Joint Statement by the European Paediatric Soft Tissue Sarcoma Study Group, the Cooperative Weichteilsarkom Studiengruppe and the Oncology Task Force of the European...

Abstract

Appropriate imaging is essential in the treatment of children and adolescents with rhabdomyosarcoma. For adequate stratification and optimal individualised local treatment utilising surgery and radiotherapy, high-quality imaging is crucial. The paediatric radiologist, therefore, is an essential member of the multi-disciplinary team providing clinical care and research. This manuscript presents the European rhabdomyosarcoma imaging guideline, based on the recently developed guideline of the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG) Imaging Committee. This guideline was developed in collaboration between the EpSSG Imaging Committee, the Cooperative Weichteilsarkom Studiengruppe (CWS) Imaging Group, and the Oncology Task Force of the European Society of Paediatric Radiology (ESPR). MRI is recommended, at diagnosis and follow-up, for the evaluation of the primary tumour and its relationship to surrounding tissues, including assessment of neurovascular structures and loco-regional lymphadenopathy. Chest CT along with [F-18]2-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET)/CT or PET/MRI are recommended for the detection and evaluation of loco-regional and distant metastatic disease. Guidance on the estimation of treatment response, optimal long-term follow-up, technical imaging settings and standardised reporting are described. This European imaging guideline outlines the recommendations for imaging in children and adolescents with rhabdomyosarcoma, with the aim to harmonise imaging and to advance patient care.

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References
1.
Vaarwerk B, Bisogno G, McHugh K, Brisse H, Morosi C, Corradini N . Indeterminate Pulmonary Nodules at Diagnosis in Rhabdomyosarcoma: Are They Clinically Significant? A Report From the European Paediatric Soft Tissue Sarcoma Study Group. J Clin Oncol. 2019; 37(9):723-730. DOI: 10.1200/JCO.18.01535. View

2.
Rosenberg A, Anderson J, Lyden E, Rodeberg D, Wolden S, Kao S . Early response as assessed by anatomic imaging does not predict failure-free survival among patients with Group III rhabdomyosarcoma: a report from the Children's Oncology Group. Eur J Cancer. 2013; 50(4):816-23. PMC: 3944684. DOI: 10.1016/j.ejca.2013.11.031. View

3.
Routh J, Dasgupta R, Chi Y, Shnorhavorian M, Tian J, Walterhouse D . Impact of local control and surgical lymph node evaluation in localized paratesticular rhabdomyosarcoma: A report from the Children's Oncology Group Soft Tissue Sarcoma Committee. Int J Cancer. 2020; 147(11):3168-3176. PMC: 7751831. DOI: 10.1002/ijc.33143. View

4.
Spijkers S, Staats J, Littooij A, Nievelstein R . Abdominal lymph node size in children at computed tomography. Pediatr Radiol. 2020; 50(9):1263-1270. PMC: 7399684. DOI: 10.1007/s00247-020-04715-z. View

5.
Cieszanowski A, Lisowska A, Dabrowska M, Korczynski P, Zukowska M, Grudzinski I . MR Imaging of Pulmonary Nodules: Detection Rate and Accuracy of Size Estimation in Comparison to Computed Tomography. PLoS One. 2016; 11(6):e0156272. PMC: 4892605. DOI: 10.1371/journal.pone.0156272. View