The Comparative Genomics and Complex Population History of Baboons

Overview

Journal Sci Adv

Specialties Biology
Science

Date 2019 Mar 12

PMID 30854422

Citations 58

Authors

Jeffrey Rogers

Muthuswamy Raveendran

R Alan Harris

Thomas Mailund

Kalle Leppala

Georgios Athanasiadis

Mikkel Heide Schierup

Jade Cheng

Kasper Munch

Jerilyn A Walker

Miriam K Konkel

Vallmer Jordan

Cody J Steely

Thomas O Beckstrom

Christina Bergey

Andrew Burrell

Dominik Schrempf

Angela Noll

Maximillian Kothe

Gisela H Kopp

Yue Liu

Shwetha Murali

Konstantinos Billis

Fergal J Martin

Matthieu Muffato

Laura Cox

James Else

Todd Disotell

Donna M Muzny

Jane Phillips-Conroy

Bronwen Aken

Evan E Eichler

Tomas Marques-Bonet

Carolin Kosiol

Mark A Batzer

Matthew W Hahn

Jenny Tung

Dietmar Zinner

Christian Roos

Clifford J Jolly

Richard A Gibbs

Kim C Worley

Affiliations

Soon will be listed here.

Abstract

Recent studies suggest that closely related species can accumulate substantial genetic and phenotypic differences despite ongoing gene flow, thus challenging traditional ideas regarding the genetics of speciation. Baboons (genus ) are Old World monkeys consisting of six readily distinguishable species. Baboon species hybridize in the wild, and prior data imply a complex history of differentiation and introgression. We produced a reference genome assembly for the olive baboon () and whole-genome sequence data for all six extant species. We document multiple episodes of admixture and introgression during the radiation of baboons, thus demonstrating their value as a model of complex evolutionary divergence, hybridization, and reticulation. These results help inform our understanding of similar cases, including modern humans, Neanderthals, Denisovans, and other ancient hominins.

Citing Articles

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Unprecedented female mutation bias in the aye-aye, a highly unusual lemur from Madagascar.

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Age- and size-related changes in hind limb muscles in two baboon species (Papio anubis and P. papio).

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