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Matthieu Muffato

Explore the profile of Matthieu Muffato including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 12682
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Recent Articles
1.
Yu D, Ren Y, Uesaka M, Beavan A, Muffato M, Shen J, et al.
Nat Ecol Evol . 2024 Jan; 8(3):519-535. PMID: 38216617
Polyploidy or whole-genome duplication (WGD) is a major event that drastically reshapes genome architecture and is often assumed to be causally associated with organismal innovations and radiations. The 2R hypothesis...
2.
Muffato M, Louis A, Nguyen N, Lucas J, Berthelot C, Crollius H
Nat Ecol Evol . 2023 Jan; 7(3):355-366. PMID: 36646945
Ancestral sequence reconstruction is a fundamental aspect of molecular evolution studies and can trace small-scale sequence modifications through the evolution of genomes and species. In contrast, fine-grained reconstructions of ancestral...
3.
Contreras-Moreira B, Naamati G, Rosello M, Allen J, Hunt S, Muffato M, et al.
Methods Mol Biol . 2022 Jan; 2443:27-55. PMID: 35037199
Ensembl Plants ( http://plants.ensembl.org ) offers genome-scale information for plants, with four releases per year. As of release 47 (April 2020) it features 79 species and includes genome sequence, gene...
4.
Yates A, Allen J, Amode R, Azov A, Barba M, Becerra A, et al.
Nucleic Acids Res . 2021 Nov; 50(D1):D996-D1003. PMID: 34791415
Ensembl Genomes (https://www.ensemblgenomes.org) provides access to non-vertebrate genomes and analysis complementing vertebrate resources developed by the Ensembl project (https://www.ensembl.org). The two resources collectively present genome annotation through a consistent set...
5.
Cunningham F, Allen J, Allen J, Alvarez-Jarreta J, Amode M, Armean I, et al.
Nucleic Acids Res . 2021 Nov; 50(D1):D988-D995. PMID: 34791404
Ensembl (https://www.ensembl.org) is unique in its flexible infrastructure for access to genomic data and annotation. It has been designed to efficiently deliver annotation at scale for all eukaryotic life, and...
6.
Howe K, Achuthan P, Allen J, Allen J, Alvarez-Jarreta J, Amode M, et al.
Nucleic Acids Res . 2020 Nov; 49(D1):D884-D891. PMID: 33137190
The Ensembl project (https://www.ensembl.org) annotates genomes and disseminates genomic data for vertebrate species. We create detailed and comprehensive annotation of gene structures, regulatory elements and variants, and enable comparative genomics...
7.
Gemmell N, Rutherford K, Prost S, Tollis M, Winter D, Macey J, et al.
Nature . 2020 Aug; 585(7823):E3. PMID: 32811988
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
8.
Gemmell N, Rutherford K, Prost S, Tollis M, Winter D, Macey J, et al.
Nature . 2020 Aug; 584(7821):403-409. PMID: 32760000
The tuatara (Sphenodon punctatus)-the only living member of the reptilian order Rhynchocephalia (Sphenodontia), once widespread across Gondwana-is an iconic species that is endemic to New Zealand. A key link to...
9.
Altenhoff A, Garrayo-Ventas J, Cosentino S, Emms D, Glover N, Hernandez-Plaza A, et al.
Nucleic Acids Res . 2020 May; 48(W1):W538-W545. PMID: 32374845
The identification of orthologs-genes in different species which descended from the same gene in their last common ancestor-is a prerequisite for many analyses in comparative genomics and molecular evolution. Numerous...
10.
Yates A, Achuthan P, Akanni W, Allen J, Allen J, Alvarez-Jarreta J, et al.
Nucleic Acids Res . 2019 Nov; 48(D1):D682-D688. PMID: 31691826
The Ensembl (https://www.ensembl.org) is a system for generating and distributing genome annotation such as genes, variation, regulation and comparative genomics across the vertebrate subphylum and key model organisms. The Ensembl...