Muthuswamy Raveendran
Overview
Explore the profile of Muthuswamy Raveendran including associated specialties, affiliations and a list of published articles.
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Articles
56
Citations
1053
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Recent Articles
1.
Wang R, Pena-Garcia Y, Raveendran M, Harris R, Nguyen T, Gingras M, et al.
PLoS Biol
. 2025 Feb;
23(2):e3003015.
PMID: 39919095
Every mammal studied to date has been found to have a male mutation bias: male parents transmit more de novo mutations to offspring than female parents, contributing increasingly more mutations...
2.
Orkin J, Kuderna L, Hermosilla-Albala N, Fontsere C, Aylward M, Janiak M, et al.
Nat Ecol Evol
. 2024 Dec;
9(1):42-56.
PMID: 39730835
Ecological variation and anthropogenic landscape modification have had key roles in the diversification and extinction of mammals in Madagascar. Lemurs represent a radiation with more than 100 species, constituting roughly...
3.
Pena-Garcia Y, Wang R, Raveendran M, Harris R, Samollow P, Rogers J, et al.
bioRxiv
. 2024 Dec;
PMID: 39713461
Article Summary: This study investigates the germline mutation rate in the gray short-tailed opossum, a marsupial with early reproductive maturity. By sequencing 22 families, we report the lowest mutation rate...
4.
Wang J, Wang M, Moshiri A, Harris R, Raveendran M, Nguyen T, et al.
Nat Commun
. 2024 Jul;
15(1):5658.
PMID: 38969634
Understanding and treating human diseases require valid animal models. Leveraging the genetic diversity in rhesus macaque populations across eight primate centers in the United States, we conduct targeted-sequencing on 1845...
5.
Prall T, Karl J, Varghese J, Baker D, Minor N, Raveendran M, et al.
J Immunol
. 2024 Apr;
212(11):1754-1765.
PMID: 38639635
Mauritian-origin cynomolgus macaques (MCMs) serve as a powerful nonhuman primate model in biomedical research due to their unique genetic homogeneity, which simplifies experimental designs. Despite their extensive use, a comprehensive...
6.
Wang Q, Clark K, Tiwari R, Raju N, Tharp G, Rogers J, et al.
Cell
. 2024 Mar;
187(5):1223-1237.e16.
PMID: 38428396
While CD4 T cell depletion is key to disease progression in people living with HIV and SIV-infected macaques, the mechanisms underlying this depletion remain incompletely understood, with most cell death...
7.
Harris R, Raveendran M, Warren W, LaDeana H, Tomlinson C, Graves-Lindsay T, et al.
Genes (Basel)
. 2023 Dec;
14(12).
PMID: 38137007
The common marmoset () is one of the most widely used nonhuman primate models of human disease. Owing to limitations in sequencing technology, early genome assemblies of this species using...
8.
Kuderna L, Ulirsch J, Rashid S, Ameen M, Sundaram L, Hickey G, et al.
Nature
. 2023 Nov;
625(7996):735-742.
PMID: 38030727
Noncoding DNA is central to our understanding of human gene regulation and complex diseases, and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in...
9.
Kuderna L, Gao H, Janiak M, Kuhlwilm M, Orkin J, Bataillon T, et al.
Science
. 2023 Jun;
380(6648):906-913.
PMID: 37262161
The rich diversity of morphology and behavior displayed across primate species provides an informative context in which to study the impact of genomic diversity on fundamental biological processes. Analysis of...
10.
Gao H, Hamp T, Ede J, Schraiber J, McRae J, Singer-Berk M, et al.
Science
. 2023 Jun;
380(6648):eabn8153.
PMID: 37262156
Personalized genome sequencing has revealed millions of genetic differences between individuals, but our understanding of their clinical relevance remains largely incomplete. To systematically decipher the effects of human genetic variants,...