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James Else

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Articles 14
Citations 939
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Recent Articles
1.
Rogers J, Raveendran M, Harris R, Mailund T, Leppala K, Athanasiadis G, et al.
Sci Adv . 2019 Mar; 5(1):eaau6947. PMID: 30854422
Recent studies suggest that closely related species can accumulate substantial genetic and phenotypic differences despite ongoing gene flow, thus challenging traditional ideas regarding the genetics of speciation. Baboons (genus )...
2.
Sundaravaradan V, Saleem R, Micci L, Gasper M, Ortiz A, Else J, et al.
PLoS Pathog . 2013 Jul; 9(6):e1003441. PMID: 23825945
Studying SIV infection of natural host monkey species, such as sooty mangabeys, has provided insights into the immune changes associated with these nonprogressive infections. Mangabeys maintain immune health despite high...
3.
Robledo R, Lorenz J, Beck J, Else J, Bender P
Coll Antropol . 2013 May; 37(1):245-50. PMID: 23697280
Twelve autosomal dinucleotide repeat loci were analyzed in chimpanzees genomes by DNA amplification using primers designed for analysis of human loci. The markers span the entire length of human chromosomes...
4.
Micci L, Cervasi B, Ende Z, Iriele R, Reyes-Aviles E, Vinton C, et al.
Blood . 2012 Sep; 120(19):3925-35. PMID: 22990011
IL-21 regulates Th17 cell homeostasis, enhances the differentiation of memory B cells and antibody-secreting plasma cells, and promotes the maintenance of CD8(+) T-cell responses. In this study, we investigated the...
5.
Vanderford T, Slichter C, Rogers K, Lawson B, Obaede R, Else J, et al.
Blood . 2012 May; 119(24):5750-7. PMID: 22550346
A key feature differentiating nonpathogenic SIV infection of sooty mangabeys (SMs) from pathogenic HIV/SIV infections is the rapid resolution of type I IFN (IFN-I) responses and IFN-stimulated gene expression during...
6.
Paiardini M, Cervasi B, Reyes-Aviles E, Micci L, Ortiz A, Chahroudi A, et al.
Nat Med . 2011 Jun; 17(7):830-6. PMID: 21706028
Naturally simian immunodeficiency virus (SIV)-infected sooty mangabeys do not progress to AIDS despite high-level virus replication. We previously showed that the fraction of CD4(+)CCR5(+) T cells is lower in sooty...
7.
Chahroudi A, Meeker T, Lawson B, Ratcliffe S, Else J, Silvestri G
J Virol . 2011 Apr; 85(12):5757-63. PMID: 21450815
Mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) occurs in utero, intrapartum, and through breastfeeding, with a cumulative rate of transmission of 35 to 40%. As a result, ∼...
8.
Taaffe J, Chahroudi A, Engram J, Sumpter B, Meeker T, Ratcliffe S, et al.
J Virol . 2010 Mar; 84(11):5476-84. PMID: 20335252
Natural simian immunodeficiency virus (SIV) infection in sooty mangabeys (SMs) typically does not result in AIDS, despite high-level viremia and significant depletion of mucosal CD4(+) T cells. Here, we report...
9.
Klatt N, Shudo E, Ortiz A, Engram J, Paiardini M, Lawson B, et al.
PLoS Pathog . 2010 Feb; 6(1):e1000747. PMID: 20126441
While CD8+ T cells are clearly important in controlling virus replication during HIV and SIV infections, the mechanisms underlying this antiviral effect remain poorly understood. In this study, we assessed...
10.
Paiardini M, Cervasi B, Engram J, Gordon S, Klatt N, Muthukumar A, et al.
Blood . 2008 Oct; 113(3):612-21. PMID: 18832134
Bone marrow (BM) is the key hematopoietic organ in mammals and is involved in the homeostatic proliferation of memory CD8(+) T cells. Here we expanded on our previous observation that...