A Pendant Peptide Endows a Sunscreen with Water-resistance

Overview

Journal Org Biomol Chem

Publisher Royal Society of Chemistry

Specialties Biochemistry
Chemistry

Date 2018 Sep 27

PMID 30256375

Citations 7

Authors

Aubrey J Ellison

Ronald T Raines

Affiliations

Soon will be listed here.

Abstract

Ultraviolet light causes skin cancer. Salicylic acid and other molecular filters absorb damaging radiation but are washed away readily. Conjugation to a collagen mimetic peptide is shown to retain salicylic acid on collagen-containing skin surrogates after repeated washing. This strategy, which is highly modular, could enhance the water-resistance of sunscreens.

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The Chemistry and Biology of Collagen Hybridization.

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Bifunctional Peptide that Anneals to Damaged Collagen and Clusters TGF-β Receptors Enhances Wound Healing.

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Cyclic Peptide Mimetic of Damaged Collagen.

Ellison A, Tanrikulu I, Dones J, Raines R Biomacromolecules. 2020; 21(4):1539-1547.

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